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Staff
Dr. Merideth is a staff clinician in the Office of the Clinical Director and program director for both the NHGRI Medical Biochemical Genetics Fellowship and
NHGRI Clinical Biochemical Genetics Fellowship.
Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
… - especially young children - easily overwhelmed by bacterial infections. A baby born with sickle cell disease …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… to a pattern of DNA sequences that appears frequently in bacterial DNA. Scientists believe the CRISPR sequences …
Educational Resources
The plasma membrane, also called the cell membrane, is the membrane found in all cells that separates the interior of the cell from the outside environment.
… the interior of the cell from the outside environment. In bacterial and plant cells, a cell wall is attached to the …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… of a modified viral vector or a linear fragment of bacterial DNA. After the artificial DNA is inserted, the …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… for high-quality assembly. This work has revolutionized bacterial genome assembly, giving complete and accurate …
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… PROBLEM section: When the F factor is integrated into the bacterial chromosome, can it still act as a donor in a …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… the environment, or national security. The first synthetic bacterial genome was completed in 2008 with the synthesis of …