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Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… A promoter is a sequence of DNA needed to turn a gene on or off. … Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), … as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and …
News Release
NIH will award nearly $80 million to support the establishment of the Mendelian Genomics Research Consortium and the development of novel methods and approaches that help researchers identify the genetic causes of single-gene diseases.
… help researchers identify the genetic causes of single-gene diseases. Over 400 million people worldwide have been … generally thought to be caused by mutations in a single gene. The awards will be provided by the National Human … research community to perform more robust Mendelian gene discovery projects. The new clinical centers will be led …
Outreach
The USA Science and Engineering Festival is an opportunity to take part in hands-on genetics and genomics activities.
… Tree . The CRISPR Corner Are you familiar with the term “gene editing”? Gene editing is a hot topic of discussion and has many … fields such as research, biotechnology, and medicine. This activity will explain the science behind one specific gene …
News Release
NHGRI researchers have discovered clues to the possible cause of recurring, non-contagious fevers and sores that affect only children. Several genes have been implicated with the syndrome, known as PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis), which could lead to new treatments.
… that the syndrome is caused by mutations in a single gene, they considered the possibility that multiple genes are … symptom – canker sores. The group looked into whether the gene variants known to be associated with those diseases were … and canker sores. The strongest association was with the gene IL12A , which encodes an inflammation-related protein …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… A transcriptome is a collection of all the gene readouts present in a cell. … words, copied - into RNA ( ribonucleic acid ) . These gene readouts are called transcripts, and a transcriptome is a collection of all the gene readouts present in a cell. There are various kinds of …
News Release
NIH will award $38.5 million over five years to the Developmental Genotype-Tissue Expression (dGTEx) project, which aims to build a widely available resource of human developmental gene expression in a multitude of tissues for use in basic and clinical research.
… The project will increase our understanding of how gene expression is regulated over time. … of high-quality tissue samples and information on gene expression — important resources that scientists needed … It also established a resource for researchers to explore gene expression in many different tissues to understand the …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Genes, Cancer, Heart Disease, Gene-environment Interactions … that is more directly caused by mutations in a single gene. Common examples of complex genetic diseases include …
For Health Professionals
ISCC-PEG working groups that are no longer active. Information is kept for historical purposes.
About NHGRI
The Genomics and Society Working Group advises on planning and priorities for genomics and society activities at NHGRI.
Educational Resources
Codominance is a relationship between two versions of a gene.
… Codominance is a relationship between two versions of a gene. … of inheritance in which two versions (alleles) of the same gene are expressed separately to yield different traits in an … Codominance is a relationship between two versions of a gene. …