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Educational Resources
Genetic testing is the use of a laboratory test to look for genetic variations associated with a disease.
… performed in the context of medical care, ancestry studies or forensics. In a medical setting, the results of a …
Staff
Lisa Garrett is an associate investigator and director of the NHGRI Transgenic Mouse Core.
… Texas. Following completion of her undergraduate studies, she received technical training at the University of … models of cancer. At this time, she started her graduate studies at Hood College in Frederick and received her Masters … generating targeted insertions and other applications for studies in transgenic mice. … The NHGRI Embryonic Stem Cell …
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… Dr. Stewart studies phenotypes and genetic determinants of familial … affected individuals. His research group established the association among a variety of novel NF1 phenotypes, … 1: genetic, functional and clinical evidence of a novel association. Cancer Research , 69 (18): 7393-7401. 2009. [ …
Staff
Dr. Heidi Parker is an Associate Investigator in the Comparative Genetics Section of the Cancer Genetics and Comparative Genomics Branch, NHGRI.
… and Comparative Genomics Branch at the National Human Genome Research Institute of NIH. She earned her Ph.D. from … predisposition and breed sharing combined with genome-wide association, to find the inherited loci associated with high …
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… In a new study, researchers at the National Human Genome Research Institute (NHGRI) have generated the largest … The researchers used whole genome sequencing and genome-wide association studies to identify genomic variants associated …
Staff
Dr. Michael Erdos is an Associate Investigator in the Molecular Genetics Section of the Center for Precision Health Research.
… T2D. Over 90% of these fall in non-coding regions of the genome, making it difficult to determine what gene has its … not attainable from the FUSION subjects. The aim of these studies is to compile the knowledge gained from studying … colleagues are employing this system in CRISPRi -genome wide gene inhibition experiments to identify critical genes …
Educational Resources
A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
Staff
Dr. Tyra Wolfsberg is the associate director of the Bioinformatics and Scientific Programming Core at the National Human Genome Research Institute.
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… and retroviral integration sites to the annotation of the genome of the ctenophore Mnemiopsis leidyi . Dr. Wolfsberg … and safety of retroviruses used as vectors in gene therapy studies. More recently, her group has expanded the pipeline … zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res , 23(4):727-35. 2013. …
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
Educational Resources
Positional cloning is a laboratory technique used to locate the position of a disease-associated gene along the chromosome.