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News Release
ENCODE program directors in the Division of Genome Sciences turned to Reddit to answer questions from the Reddit community.
… looked at ENCODE samples from cells immortalized with a virus (EBV) and analyzed the viral DNA in the data (ENCODE …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
…  showed that it was possible to create the polio virus from scratch and brought attention to the risk that … genome editing technologies. As the synthesis of the polio virus demonstrates, there are also biosecurity concerns …
FAQ
Addressing the COVID-19 pandemic and what it means to the pediatric mitochondrial disease community.
… When children with mitochondrial disease get sick with any virus, this experience can be life-threatening, as their …
The Genomics Landscape
In the May 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details how NIH is ramping up research on COVID-19; NHGRI's expansion of its Genome Technology Program; and the the DiY Genome: Unlocking Life's Code exhibition toolkit.
… are available that provide relevant information about the virus and the disease it causes, such as those at the Centers …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2020.
The Genomics Landscape
In the July 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 10th anniversary of the Undiagnosed Diseases Program.
News Release
NHGRI has selected James Thomas, Ph.D., as the new director of the NIH Intramural Sequencing Center (NISC), to will oversee the importation and use of DNA sequencing technologies, protocols and analyses, ensuring that NIH investigators have access to cutting-edge DNA sequencing methods and specialized genomics protocols to meet their research needs.Â
… understand the molecular basis of the SARS-CoV-2 virus and immune response. NISC also provided DNA sequencing …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… and immunologic organ. Signals such as cytokines, virus, PAMPs and DAMPs activate Kupffer cells in the liver. … C.P., McGuire, P.J. Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model …
Genetic Disorders
Cystic fibrosis is a genetic disease that causes the body to produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas.
… to a patient with CF. Researchers modified a common cold virus to act as a delivery vehicle - or "vector"- carrying …