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News Release
The TCGA network describes uterine and bile duct cancer.
… the molecular characteristics of breast cancer by African and European Ancestry. This paper identifies … of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… 50 the chance of having prostate cancer increases rapidly. African-American background: Prostate cancer is more common in African American men, than in men of other racial backgrounds. African American men are more often diagnosed with prostate …
The Genomics Landscape
In the October 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., introduces us to new scientific director Charles Rotimi, Ph.D., his background and prior accomplishments.
… His expertise in the unique genomic diversity of African populations has contributed to the advancement of … Notably, Charles engineered the successful engagement of African communities for the International Haplotype Mapping … expanded genomics-based studies of human disease on the African continent. As a leading genetic epidemiologist and …
News Release
NHGRI researchers will present four platform talks and 55 posters to highlight the institute's diverse portfolio at the 65th annual meeting of ASHG.
… sequencing identifies miRNAs in peripheral blood of African Americans related to metabolic syndrome and abdominal … of Sequence Variants in a Population-based Study of African Americans: Implications for report of incidental … the distribution of HDL-cholesterol in West Africans and African Americans. (Complex Traits and Polygenic Disorders) …
Staff
Dr. Rongling Li is an epidemiologist and program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
… Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. J Am Coll Cardiol . 69(12):1564-1574. doi: … unique venous thromboembolism-susceptibility variants in African-Americans. Thromb Haemost . doi: … Approach of 16q12.2/ FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional …
Research at NHGRI
An international investigation into the genetics of severe acute malnutrition in children.
… novel genetic variants and unique patterns of admixture in African and other diverse ancestry populations who harbor the …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… life. SCD affects approximately 100,000 Americans. Among African Americans, 1 in every 365 is born with sickle cell … with sickle cell trait. Although the risk is greater among African Americans, many people are affected by both SCD and …
NEWS RELEASE
Final outcomes from the most comprehensive analysis to-date of humans and their microbiomes definitively link microbes and microbial activities with health problems.
… Prevention , in 2016, the rate of premature birth among African-American women was 14% compared to white women at 9% … their risk for preterm birth, with a particular focus on African-American women. The project enrolled and followed a … that during the early stages of pregnancy, women (mostly African-American) who experienced preterm birth had …
The Genomics Landscape
In the November 5, 2020 edition of The Genomics Landscape, Dr. Eric Green focuses on the 2020 Strategic Vision.
… results from their efforts to increase genomic data from African populations. The paper , entitled “High depth African genomes inform human migration and health,” includes … of whole-genome sequences of 426 individuals from 13 African countries, which together represent 50 …
Archive
… The African Diaspora: Integrating Culture, Genomics and History … Archive …