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- Ethical, Legal and Social Implications (ELSI) Research Program1
- Genomics-Enabled Learning Health Systems (gLHS)1
- Genome Technology Program3
- Impact of Genomic Variation on Function (IGVF) Consortium1
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)2
- Developmental Genotype-Tissue Expression (dGTEx)1
Staff
Stacie Anderson is an associate director in the Office of Scientific Core Facilities and is also the director of the Flow Cytometry Core.
… by the Core include planning, design, execution, and analysis of experiments involving flow cytometry, permitting … analyses include: Cell survival/apoptosis, proliferation, DNA content, cell cycle analyses and cytolysis. The Core is … … Stacie Anderson, flow cytometry, single cell analyses, DNA analysis … Stacie Anderson is an associate director in …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… , scientists have set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how … that make the genome work. Chemical tags that stick to the DNA impact chromatin organization and which genes are …
Educational Resources
Gene mapping is the process of establishing the locations of genes on the chromosomes.
… of genes on the chromosomes. … Chromosomes, Linkage Analysis, Genome Sequencing, DNA Sequencing, Chromosomes … Gene mapping refers to the …
Fact Sheets
Polymerase chain reaction (PCR) is a technique used to "amplify" small segments of DNA.
… (PCR) is a technique used to "amplify" small segments of DNA. … Sometimes called "molecular photocopying," the … technique used to "amplify" - copy - small segments of DNA. Because significant amounts of a sample of DNA are necessary for molecular and genetic analyses, studies …
Educational Resources
Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded.
… (RNA) … Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. … Cell, Genetic Code, Deoxyribonucleic Acid (DNA), Protein, Uracil, Adenine, Cytosine, Guanine, Messenger …
Fact Sheets
Data used to estimate the cost of sequencing the human genome over time since the Human Genome Project.
… Institute (NHGRI) has tracked the costs associated with DNA sequencing performed at the sequencing centers funded by … as an important benchmark for assessing improvements in DNA sequencing technologies and for establishing the DNA … NHGRI Genome Sequencing Program. Here, NHGRI provides an analysis of these data, which gives one view of the …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … Shotgun …
Educational Resources
A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.”
… Base Pair … A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.” … Genetic Code, Nucleotides, Amino Acids, … Cytosine, Guanine, Thymine, Base Pairs, Double Helix, DNA … A base pair consists of two complementary DNA …