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News Release
NIH issues a final Genomic Data Sharing policy to speed the translation of data into knowledge, improve health and protect patient privacy.
… September 2013. The GDS policy can be traced to the Human Genome Project, completed in 2003, which required rapid and … The GDS policy is an extension of and replaces the Genome-Wide Association Studies (GWAS) data sharing policy. Since 2007, the GWAS … Genomic data sharing policy, GDS, data to knowledge, Human Genome Project, GWAS policy, dbGaP, Informed consent …
News Release
NIH researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced.
… Development, senior investigator in the National Human Genome Research Institute (NHGRI) Center for Precision Health … copy of over 200 protein-coding genes to that person’s genome, which causes difficulties with learning, speech and … standard for Down syndrome research, used in preclinical studies for nearly 30 years. Along with some successful …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National … 5, 2015, and to be published in the July 2015 issue of Genome Research , the researchers reported that the … to both generate mutants for all genes in the zebrafish genome and carry out large-scale phenotyping, they noted in …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new molecular … by the National Cancer Institute and the National Human Genome Research Institute, both parts of the National … information about NHGRI can be found at http://www.genome.gov . NCI leads the National Cancer Program and the …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… have discovered over 100 new regions of the human genome, also known as genomic loci , that appear to … in Nature Genetics , is one of the largest such genomic studies of blood pressure to date, including data from over 1 … the researchers combined four large datasets from genome-wide association studies of blood pressure and hypertension. …
Fact Sheets
Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.
… Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each … An organism's complete set of DNA is called its genome. Virtually every single cell in the body contains a … billion DNA base pairs, or letters, that make up the human genome. With its four-letter language, DNA contains the …
Research at NHGRI
The Genetics and Molecular Biology Branch uses genomic technologies to study the human genome and other organisms and disease mechanisms.
… Branch uses genomic technologies to study the human genome and other organisms and disease mechanisms. …
News Release
By considering mixed genetic lineages, NHGRI researchers demonstrated that previously inferred links between a genomic variant that helps digest lactose and traits such as a person’s height and cholesterol level may not be valid.
… Researchers have found that previous studies analyzing the genomes of people with European … mixed genetic lineages, researchers at the National Human Genome Research Institute (NHGRI), part of the National … as admixture. As such, the results from previous genome-wide association studies that do not account for admixture in …
Clinical Research
An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home Participation).
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) researchers and their … regulates the expression of other genes throughout the genome. In addition, the researchers looked at patterns of …