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Fact Sheets
Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.
… associated with body overgrowth and increased risk of cancer; Prader-Willi syndrome, associated with poor muscle … changes can lead to uncontrolled growth, a hallmark of cancer, or to a failure of the immune system to destroy … treating patients with the drug temozolomide, which kills cancer cells by adding methyl groups to DNA. In some cases, …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… BRCA1, BRCA2, Cancer, Oncogene, Cell, Gene, Mutation … Such mutations may contribute to the development of a cancer. …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Genes, Cancer, Heart Disease, Gene-environment Interactions … genetic diseases include heart disease, diabetes, and cancer. …
Educational Resources
A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… Mutagen, DNA Mutation, DNA Replication, Cancer …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
… DNA Sequence, Cancer, PCR, Polymerase Chain Reaction, Laboratory Experiment … an increase in the number of copies of a gene in a genome. Cancer cells, for example, sometimes produce multiple copies …
Event
NHGRI, National Institute of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application interactive webinar for the Multi-Omics for Health and Disease program funding opportunity announcements (FOAs): RFA-HG-22-008,
RFA-HG-22-009 and RFA-HG-22-010.
… of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application … of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application … of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application …
Educational Resources
Apoptosis is the process of programmed cell death.
… Programmed Cell Death, Development, DNA Repair, Cancer, Tumor, Cell Division … beyond repair. Apoptosis also plays a role in preventing cancer. If apoptosis is for some reason prevented, it can …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… challenge health care providers face in treating prostate cancer is distinguishing the aggressive, potentially … way to identify a specific subgroup of prostate cancer tumors with a known treatment option," said Elaine … the study's corresponding author and chief of NHGRI's Cancer Genetics and Comparative Genomics Branch . "New …
Staff
Dr. Bailey-Wilson is a scientist emeritus in NHGRI's Division of Intramural Research.
… and is especially interested in risk factors for lung cancer, prostate cancer, eye disorders, autism and oral clefts. Dr. … served on many scientific advisory boards including the Cancer Family Registry CFRCCS Advisory Board, the World Trade … for mendelian inheritance in the pathogenesis of lung cancer. J Nat Cancer Inst , 82:1272-1279. 1990. [ PubMed ] …