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Dr. Simona Volpi is a program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
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… grants and contracts related to the Genotype-Tissue Expression (GTEx) Project as well as the newly established … … Simona Volpi, common diseases, Genotype-Tissue Expression Project (GTEx), NIH Common Fund … Dr. Simona Volpi …
Educational Resources
Non-coding DNA corresponds to the portions of an organism’s genome that do not code for amino acids, the building blocks of proteins.
… the building blocks of proteins. … DNA Sequence, Gene Expression, Chromosome, Non-coding DNA, Junk DNA, Genetic … serve functional roles, such as in the regulation of gene expression, while other areas of non-coding DNA have no known …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… … Cell, Deoxyribonucleic Acid (DNA), Enzyme, Gene Expression, Restriction Enzyme, Vector … Recombinant DNA …
News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… Of DNA Elements (modENCODE) Consortium studied how gene expression patterns and regulatory proteins that help … genes and regulatory elements that control gene expression. The current work builds on initial catalogs … (or readouts) in a genome. They used large amounts of gene expression data generated in the ENCODE and modENCODE …
Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, Personalized Medicine, Gene … associated with a risk for a disease or a particular trait. The method involves surveying the genomes of many … occur more frequently in those with a specific disease or trait compared to those without the disease or trait. Once …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… or off. … Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), …
Staff
Dr. Elise Feingold is a scientific program manager in NHGRI's Division of Genome Sciences.
… 1992 as a program director focused on gene discovery, gene expression and functional genomics. Since 2019, Dr. Feingold … implications for the control of gamma-globin gene expression in man . Proc Natl Acad Sci U S A , … Excellence in Genomic Science (CEGS), gene discovery, gene expression, functional genomics … Dr. Elise Feingold is a …
The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… 30 years ago. …  Researchers from the Genotype-Tissue Expression Project (GTEx) consortium, an NIH Common Fund … gene expression produced to date. The studies focus on quantitative trait loci (QTL), specifically associations between known …
Educational Resources
Translation is the process of translating the sequence of a messenger RNA (mRNA) molecule to a sequence of amino acids during protein synthesis.
… … Transcription, Base Pair, Cell, Cytoplasm, Gene, Gene Expression, Genetic Code, Messenger RNA (mRNA), Protein, …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, Personalized Medicine, Gene …