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Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… molecule called messenger ribonucleic acid, or mRNA. Next, the information contained in the mRNA molecule is translated into the "language" of amino … a template. This template strand is then transcribed into mRNA, which is a molecule that conveys vital instructions to …
The Genomics Landscape
In the June 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D. details the upcoming appointment of acting NHGRI Deputy Director, Vence Bonham Jr., J.D. and what it means for the institute.
… for disease gene mapping. … Genomics Research Gene therapy restores immune function in children with rare … COVID-19 screening guidelines Studies Confirm COVID-19 mRNA Vaccines Safe, Effective for Pregnant Women COVID-19 mRNA Vaccine Q&A with Dr. Kizzmekia S. Corbett NIH clinical …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… either by genes in the Ensembl database, or by human mRNA best BLAT (BLAST-like alignment tool) alignments in the … and which did not correspond to Ensembl genes, GenBank mRNA BLASTZ alignments, Fgenesh++ gene predictions, TwinScan …
Research Funding
The N​on-Coding Variants Program explores which variants in a region associated with a disease or trait cause the higher risk for the disease or trait
… University-Purdue University at Indianapolis Regulation of mRNA splicing by intronic genetic variants R01 CA213466 …
News Release
Three research teams funded by NIH gather data at the most basic molecular levels about the biological processes that make up the human microbiome.
… identifying the specific microbial population can guide therapy. In addition, the project aims to build a new IBD …
The Genomics Landscape
In the November 4, 2021 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., details how NHGRI researchers are emphasizing the need for diversity in genomics.
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… a synthetic type of DNA generated from messenger RNA, or mRNA, the molecule in the cell that takes information from … and instructs it to make a specific protein. By using mRNA as a template, scientists use enzymatic reactions to …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… How COVID-19 can lead to diabetes Dr. Collins explains how mRNA vaccines work and shares his health and wellness habits … Meet an inspiring researcher who helped create COVID-19 mRNA vaccines How immunity generated from COVID-19 vaccines …
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… PROBLEM section: Why can there be more then one possible mRNA sequence for a peptide sequence? #23. A gene is a … #24. The RNA message is sometimes edited. What happens to mRNA when there is no binding region of DNA to match? What is …
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… R, Strauss, JF. Increased transcription and increased mRNA stability contribute to increased GATA6 mRNA abundance in PCOS theca cells. Journal of Clinical …