Search Results
Talking Glossary
Next-generation DNA sequencing (abbreviated NGS) refers to the use of technologies for sequencing DNA that became available shortly after the completion of the Human Genome Project (which relied on the first-generation method of Sanger sequencing).
… Next-Generation DNA Sequencing … Next-generation DNA sequencing (abbreviated NGS) refers to the use of … the first-generation method of Sanger sequencing). Faster and cheaper than their predecessors, NGS technologies can …
News Release
Baylor College of Medicine. Houston and the Medical College of Wisconsin, Milwaukee will be providing DNA sequencing for the Undiagnosed Diseases Network.
… announced today that Baylor College of Medicine in Houston and the Medical College of Wisconsin in Milwaukee will be providing DNA sequencing for the Undiagnosed Diseases Network (UDN). Each … Ph.D. Researchers will establish a pipeline for functional analysis, drug discovery, and pathway identification of …
FAQ
Frequently asked questions on the webinar for the Diversity Centers for Genome Research funding opportunity announcements (FOAs): (RFA-HG-22-026 and RFA-HG-22-027.
… be a domestic institution located in the United States and its territories which:  Has received an average of less … level research? It is not expected that the projects be large such as R01 level research. Small and/or pilot genetic … the organization, implementation, and evaluation of a full-scale genomic research center Plans for recruitment and …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… Darryl Leja, NHGRI. "TCGA was the first project of its scale to characterize - at the molecular level - cancer … at NCI. The project focused not only on cancer genome sequencing, but also on different types of data analyses, … September 27-29, 2018, that will discuss the future of large-scale cancer studies, with a session focusing on the …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… sees an incomplete human genome sequence, with A, C, Ts and Gs, but is still missing some bases. She has doubts and says "Hmm, this doesn't look complete to me." … The human … with a vision. Even with new technologies, genome sequencing is still tough, time-consuming work that requires …
News Release
CMG investigators have made significant inroads in discovering genes underlying Mendelian conditions and have uncovered 470 new, previously unknown conditions.
… CMG, or others, submit DNA samples to the centers for DNA sequencing - or more specifically, exome or whole genome … were able to move exome sequencing into efficient, large-scale production. "We knew that discovery would depend on …
News Release
NHGRI has selected Adam Phillippy, Ph.D. as the founding director of the new Center for Genomics and Data Science Research within the Institute’s Intramural Research Program.
… Phillippy to provide scientific leadership and shape direction of computational genomics in institute’s … as the founding director of the new Center for Genomics and Data Science Research within the Institute’s Intramural … himself as an expert in genome sequence assembly and analysis not only within NIH but in the broader scientific …
News Release
The Telomere-to-Telomere (T2T) Consortium has generated the first truly complete sequence of a human Y chromosome - the final human chromosome to be fully sequenced.
… in human sexual development are spread across the genome and very complex, giving rise to the array of human sex … sequence particularly difficult to complete. Assembling sequencing data is like trying to read a long book cut into … of the human genome, the T2T Consortium applied new DNA sequencing technologies and sequence assembly methods, as …
Educational Resources
Linkage is the close association of genes or other DNA sequences on the same chromosome.
… sequences on the same chromosome. … DNA Sequence, Linkage Analysis, Family Health History, Chromosome … Linkage, as related to genetics and genomics, refers to the closeness of genes or other DNA …
News Release
Genomic analyses turned up genes that belong to inflammatory pathways.
… most of his days in extreme pain. He could barely walk and used a wheelchair. He saw numerous doctors in his … his lab at NHGRI. Dr. Kastner's team wanted to use genome sequencing to try to pinpoint if Rohith's condition was … somewhere else. From using mechanistic studies and genome sequencing to inform your patient care - that's unique to …