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Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… Mullikin pioneered DNA sequencing technologies during the Human Genome Project … What accomplishments in your career are you most proud of? Jim Mullikin: Of course, the Human Genome Project is one …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA …
Media Advisory
NHGRI memorializes genomics champion Rep. Louise M. Slaughter (D-N.Y.) with an annual National DNA Day lecture named in her honor.
… Kiara Palmer … Media Advisory The National Human Genome Research Institute (NHGRI) will memorialize the life and legacy of genomics champion Representative Louise M. Slaughter … who passed away in March, by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in …
News Release
Research points to the effects of nutrients in how DNA mutates in the mitochondria.
… Research points to the effects of nutrients in how DNA mutates in the mitochondria. … In a very real sense, you …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… The Big Picture Sickle cell disease is an inherited disorder … Education for Sickle Cell Disease Gene Therapy Project, which is led by NHGRI in partnership with other … materials reflect the priorities and perspectives of both individuals living with sickle cell disease and the …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… Steven Benowitz … The National Institutes of Health has awarded eight grants as part of the … genomic variants - inherited spelling changes in the DNA code - may influence gene activity and lead to disease. …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… Jeannine Mjoseth … Databases such as the 1000 Genomes Project and the Exome Aggregation Consortium (ExAC) harbor large numbers of genotypes (an individual's collection of genes). Until … predictions by re-examining individuals who donated their DNA sequence information to the database. TGAC will be based …
Research Funding
The Knockout Mouse Phenotyping Project (KOMP2) collaborates with the International Mouse Phenotyping Consortium (IMPC) to knockout and characterize all protein-coding genes in the mouse genome.
… Braun, Robert E Murray, Stephen A White, Jacqueline K The Jackson Laboratory The Jackson Laboratory Knockout Mouse Production and Phenotyping Project (JAX KOMP2) OD023222 Dickinson, Mary E Heaney, Jason D Baylor College of Medicine The BCM Knockout Mouse Production and Phenotyping …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … While some sequencing technologies produce … methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base pairs in fragments of DNA known as …
The Genomics Landscape
In the April 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 15th anniversary of National DNA Day and the '15 for 15' Celebration.
… Eric Green, M.D., Ph.D. … In the last issue of The Genomics Landscape , I described the launching of a … community will celebrate a yearly highlight - National DNA Day. On this day, students, teachers, and the public are …