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The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
…  As the sun came up on 1997, the Human Genome Project (then in its seventh of 13 years) was adding megabases of genome sequence to public databases weekly, as large-scale … need, the recently appointed chief of NHGRI’s intramural Genome Technology Branch, Eric Green, proposed the idea of …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
… 6. Treating inherited retinal disease with gene editing 7. Validation of a clinical breast cancer risk … tool for all ancestries 8. Broader access to clinical genome sequencing benefits diverse individuals with rare … for children with suspected cancer from routine whole-genome sequencing 10. Clinical signatures of genetic …
15 Ways Genomics Influences Our World
Advances in genomics are helping you access information about your genome from your home.
… in genomics are helping you access information about your genome from your home. … in their DNA and provide them with information about their genome? Advances in genomics since the Human Genome Project have led to an explosion in at-home, or … in genomics are helping you access information about your genome from your home. …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… are implicated in disease. And, here at the National Human Genome Research Institute (NHGRI), researchers are advancing … resource known as the NHGRI Zebrafish Core. The core uses genome-editing technology to intentionally introduce small … One little fish hooks genome researchers with its versatility …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… genomes have changed? Cancer is caused by changes in your genome, but advances in DNA sequencing technology are leading … group of genetic diseases that result from changes in the genome of cells in the body, leading them to grow … uncontrollably. These changes involve DNA mutations in the genome. Our cells are constantly finding and fixing mutations …
The Genomics Landscape
In the May 5, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., pays tribute to one of NHGRI’s founding staff members and current leaders, Bettie Graham, Ph.D., as she reached a truly remarkable milestone: 50 years of service in the federal government.
… in the D.C. area — I would encourage you to visit the Genome: Unlocking Life’s Code exhibition at the Smithsonian’s … and the 10th anniversary of the completion of the Human Genome Project . After traveling to 12 states and Canada, the … 96th meeting of the National Advisory Council for Human Genome Research will take place on May 16-17. The open …
Genomics 101
Find out how the rapidly emerging field of genomics is transforming our understanding of human health and enabling advances that benefit all of humankind.
… Your genome contains many important clues about you—from your … timely information about genomics research and the human genome. Our resources and partnerships help spark scientific …
The Genomics Landscape
In the January 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly developed polygenic risk scores webpage, which provides graphical and textual information about polygenic risk scores, describes polygenic traits, introduces how polygenic risk scores can be calculated, and explains how such scores can be interpreted.
… into account information about variants across a person’s genome, comparing the collection of such genomic variants in … shares NIH’s perspective on the potential of CRISPR genome-editing systems with Southwestern Medical Foundation’s … Genome: Unlocking Life's Code …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… Phenotypes (dbGaP), model organism databases (e.g., Mouse Genome Informatics and Xenbase ), and cloud repositories … Disease Genomics, Centers for Mendelian Genomics, Whole Genome Sequencing in Psychiatric Disorders, Convergent … large-scale sequence datasets. NIH is increasingly hosting genome-sequence datasets and other genomic datasets in cloud …
Human Genome Project
Record and submit a short video, capturing your thoughts/concerns/excitement about the launch of the Human Genome Project.
… marks the 30th anniversary of the launch of the Human Genome Project. NHGRI would like you to help us commemorate … feeling] about the launch of the Human Genome Project.  Francis Collins Eric Green  … I first heard of the ambitious effort called the Human Genome Project, I was …  The Human Genome Project influenced …