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News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… The funds are necessary for making advances in DNA sequencing technology and computational methods possible. As … (HGRP). “It has grown more and more important to have a high-quality, highly usable human genome reference sequence … additional diverse human genomes using state-of-the-art technologies to incorporate high-quality sequences that are …
Research Funding
The $1,000 Genome Program was a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.
… a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of … Program, which was led by Dr. Jeffery Schloss , as the Sequencing Technology Development Program Director at NHGRI, …
Staff
Dr. Gerard Bouffard directs the Bioinformatics Group at the NIH Intramural Sequencing Center (NISC).
… where he combined his interests in early genome sequencing of the Escherichia coli genome with the nascent … expedited gene discovery on this chromosome, and directed sequencing efforts in the early days of the Human Genome … exercise the capabilities of revolutionary DNA sequencing technologies and advanced information technologies. NISC …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… genome was announced by the International Human Genome Sequencing Consortium ( Finishing the euchromatic sequence of … development phase of the project aimed to develop new high throughput methods to identify functional elements. The goal …
News Release
A team of NIH-funded researchers have generated the first complete chromosome sequences from non-human primates.
… has only become possible in recent years due to new DNA sequencing technologies and analysis methods. These chromosome sequences … biology and reproduction of these endangered species.” … … High Resolution Image … Related Infographics … About NHGRI …
Media Advisory
The National Institutes of Health (NIH) will host researchers from the Telomere-to-Telomere (T2T) consortium, who have now sequenced the remaining 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two decades.
… What: Virtual press conference to announce T2T consortium sequencing a complete human genome Moderator: Eric Green, …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… the project took on a wide range of other goals, from sequencing the genomes of model organisms to developing new … Functional Analysis Develop genomic-scale technologies High-throughput oligonucleotide synthesis DNA microarrays …
About Genomics
RNA sequencing and the detection of RNA modifications have recently gained significant attention in the genomics community. New genomic methods and technologies are still needed to advance basic and clinical research into human biology and disease.
… to study RNA are becoming a standard part of the tools and technologies used in genomics! For example, by sequencing RNA and studying its many modifications, … — Eric Green (@NHGRI_Director) May 28, 2024 … RNA sequencing and the detection of RNA modifications have …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… took the practical approach of using the best-available technologies for sequencing DNA and pushing them to their absolute limits. In the end, it delivered a remarkably high-quality human genome sequence that was nearly complete, …
The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… Agency for Health (called ARPA-H). ARPA-H aims to conduct high-impact biomedical and health research with a mission “to … sequence to public databases weekly, as large-scale DNA sequencing had advanced substantially. At that time, it … NISC has experienced radical shifts in DNA sequencing technologies, research approaches, and data analysis methods, …