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The Genomics Landscape
In the April 2020 edition of The Genomics Landscape, NHGRI Director Eric Green provides an update on the final stage of the Genomics2020 strategic planning process; the NIH website for COVID-19 information, the Gene documentary debut on PBS and more.
… So, on behalf of NHGRI, I would like to offer up some genomics-related diversions. First, anticipating interest in … Second, as I mentioned in last month’s issue of The Genomics Landscape , NHGRI’s History of Genomics Program is in the midst of showcasing 30 oral …
News Release
Researchers explored patients', parents' and physicians' perspectives on the use of CRISPR-Cas9 gene-editing to reverse sickle cell disease.
… and implementation of new genetic curative therapies, into clinical treatment," said Vence L. Bonham, Jr., J.D. , … participants and work with the physicians to understand patient needs," said Mr. Bonham. Focus group participants … urged researchers to act in a manner sensitive to the patient community and suggested the research community should …
News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
… from mouse studies usually take years to translate into health care treatment, but not in this case," said … senior author and senior investigator in the NHGRI Medical Genomics and Metabolic Genetics Branch. "We can use this … a fasting challenge to model a metabolic crisis in a patient with MMA. It enabled them to identify markers that …
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… decision-making on what is the best medication for a patient. It doesn't mean that the use of race in medical care … of a drug may not be available. The third challenge is integrating precision medicine into health care systems. Health care providers and the …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… From The Genomics Landscape Originally published: January 13, 2022  … platform for family-based monogenic disease analysis) into its suite of tools, which also includes familiar tools … to a wide range of patients.  As the lines between patient care and research continue to evolve and blur, these …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… provider by collecting a DNA sample (e.g., spitting saliva into a tube) and sending it to a company. The company can … ancestry and the health of you and your family. … One way genomics research can benefit you is through the emerging … this information can lead to more questions about what genomics means for ourselves, our family members and society. …
Clinical Research
The Undiagnosed Diseases Program provide answers to patients with mysterious conditions that have long eluded diagnosis.
… 750. Patients seen or scheduled: 700. Approximate annual patient visit rate: 130. Approximate distribution of patients … genetic and biochemical mechanisms of disease and insights into normal cell biology, biochemistry and physiology. So … rare diseases Reuters July 1, 2014: NIH Pumps $43M into Undiagnosed Diseases Network to Target Rare Disorders …
Research at NHGRI
The NHGRI Office of Laboratory Animal Medicine promotes the humane care and use of animals in biomedical and behavioral research, teaching, and testing.
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… of Laboratory Animal Medicine (OLAM) promotes the humane care and use of animals in biomedical and behavioral … and guidelines to NHGRI investigators on the proper care, use and humane treatment of research animals. OLAM is responsible for housing and care of research animals and for enhancing their well-being. …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… Genomics is transforming how we study, diagnose and treat … where doctors can gather enough information from just one patient to try a new therapy. Such trials are aided by … grow very fast and die, they release some of their DNA into the bloodstream. We now have tests that are sensitive …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… Genomics is altering a genome with unparalleled efficiency … the latter, scientists will remove blood stem cells from a patient with sickle cell disease, edit the genome of those … cell mutation, and then re-insert the modified cells into the person's bone marrow. Since there are still no cures …