Search Results
Talking Glossary
RNA-seq, short for RNA sequencing, is a method for sequencing an entire set of RNA molecules.
… RNA-seq (RNA Sequencing) … RNA-seq, short for RNA sequencing, is a method … in the tissue or cell sample, copying those RNAs into DNA and then sequencing the resulting DNA molecules. RNA-seq helps researchers determine which …
The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… genome sequence to public databases weekly, as large-scale DNA sequencing had advanced substantially. At that time, it … and medicine. From the beginning, NISC emphasized the generation of the highest data quality possible and the … This included the importation of the powerful new “next-generation” DNA sequencing technologies as they matured …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… that shows the physical locations of genes and other DNA sequences of interest. … Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional Cloning … A physical map, as related to … of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or genome. A …
Talking Glossary
Cell-free DNA testing is a laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most often to look for genomic variants associated with a hereditary or genetic disorder.
… Cell-Free DNA Testing … Cell-free DNA testing is a laboratory method that involves analyzing free (i.e., non-cellular) DNA contained within a biological sample, most often to look …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… regions of similarity and difference. … Identifying DNA sequences that have been "conserved" - that is, preserved … between species and the corresponding differences in their DNA, scientists can better understand how the appearance, … biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) aims to identify all functional elements in the human and mouse genomes.
… ENCODE ChIP-seq pipeline using endogenously tagged human DNA-associated proteins UM1 HG009411 Charles Lee The Jackson … Encoding genomic architecture in the encyclopedia: linking DNA elements, chromatin state, and gene expression in 3D U01 … after spearheading program to build encyclopedia of DNA elements, ENCODE February 10, 2023 Reddit "Ask Me …
Outreach
The DNA Day Starter Kit contains all of the materials you need to plan your classroom or community event.
… Certificate and Fillable Flyer Logo Package … The DNA Day Starter Kit contains a style guide and all of the … success. … Contact us at dnaday@nih.gov . … Questions? … DNA Day Starter Kit … The DNA Day Starter Kit contains all of the materials you need to …
News Release
April 25, 2023 marks the 20th anniversary of the completion of the Human Genome Project and the 70th anniversary of the discovery of DNA’s double-helical structure, milestones being celebrated as part of National DNA Day.
… National DNA Day commemorates Human Genome Project’s completion and … said Dr. Green. “The students from Lime Kiln represent the next generation of genomic professionals who will help transform …
Educational Resources
A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique.
… Primer … A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique. … Deoxyribonucleic Acid (DNA), Gene Amplification, Hybridization, Polymerase Chain … in a very short timeframe. Primers are also used in DNA sequencing and other experimental processes. … A primer is a …
Educational Resources
Southern blotting is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample.
… is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample. … Deoxyribonucleic Acid (DNA), Electrophoresis, Northern Blot, Probe, Restriction … blot analysis is a laboratory method used to study DNA. Specifically, purified DNA from a biological sample …