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The Genomics Landscape
In the October 2019 edition of The Genomics Landscape, NHGRI Director Eric Green focuses on recent efforts to make the human genome reference sequence useful to basic and clinical researchers and how increasing the representation of human genomic variation will remain key components of NHGRI’s Human Genome Reference Program.
… segments of DNA in some regions; for example, the sequences at the ends and centers of the human chromosomes … researchers a set of coordinates that allow new matching sequences to be aligned and organized. Such a reference must … will generate at least 350 high-quality reference genome sequences, a subset of which will be completed (end-to-end) …
Educational Resources
Epigenetics is an emerging field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism.
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … … (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are … (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … …
Outreach
The Genome: Unlocking Life's Code exhibition celebrates the 10th anniversary of the initial sequencing of the human genome.
News Release
NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about the migration of humans to the area.
About Genomics
Resources for understanding the first truly complete sequence of the Y chromosome, the final human chromosome to be fully sequenced.
… human genome sequence 20 years ago, gaps were left in the sequences of every chromosome, and in the race to sequence …
News Release
The goat has contributed its DNA to a new method for high-quality, low-cost genome reconstruction, one that will be useful for reading human and other genomes.
News Release
Evaluating genetic features of inherited diseases by sequencing the genetic code helps with the cost and time challenges in medical practice.
News Release
North Asians may be more closely related to Eastern and Northern Europeans than previously thought.
… (NHGRI), made the connection by comparing the whole-genome sequences of 175 ethnic Mongolians to existing genetic …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.