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Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… interaction with several different proteins, including the transcription factor JunD, and its requirement in endodermal …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… Statistical Models to Investigate Long-Distance QTL Transcription Regulation Audrey Q. Fu, Ph.D., University of Chicago, Causal …
Staff
Dr. Francis Collins is a senior investigator in Center for Precision Health Research.
… P, Stitzel ML, Collins FS, Kitzman JO, Parker SCJ. A Transcription Start Site Map in Human Pancreatic Islets … Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants . Proc … P, Freedman M, Siciliano MJ, Collins FS. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy …
News Release
NHGRI awards $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate.
Media Availability
New research provides a better understanding of some of the genetic and cellular changes in pathways and processes involved in Autism Spectrum Disorder.
… off, and the formation of neural connections in the brain. Transcription. Instructions embedded in genes must be … or read, to build proteins, the workhorse of the cell. Transcription mistakes can affect a wide range of important …
Educational Resources
An intron is a portion of a gene that does not code for amino acids.
… not remain in the final mature mRNA molecule following transcription of that gene and does not code for amino acids …
Genomics Teaching Tool
An activity that demonstrates how DNA can be isolated from a strawberry using common household items.
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.
… RNA to double-stranded DNA in a process called reverse transcription. The two DNA template strands are then …
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… year used LINCS data to identify the role of a critical transcription regulator, heat shock factor 1 (HSF1), in …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… that form a dimer for DNA binding and gene expression regulation, are frequent targets of such chromosome … Sood, has used zebrafish to study the roles of several transcription factor genes in hematopoiesis, such as runx1 , … Freedman M, Siciliano MJ, and Collins FS. Fusion between transcription factor CBFb/PEBP2b and a myosin heavy chain in …