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News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… of mentor Dr. Robert J. Arceci, Dr. Heuston used in vitro functional assays and in vivo rodent models to identify … aims to create a catalogue of functionally-defined genomic elements that influence the pathophysiology of …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… expression, as well as surrogate markers of regulatory elements, in different cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory network … methods with catalogs of genomic data to understand what elements are controlling what genes, in what cell types. The …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… of Michigan, Ann Arbor, Global Discovery and Validation of Functional Regulatory Elements James Bentley Brown, Ph.D., University of … National Laboratory, Berkeley, Nonparametric Methods for Functional and Translational Genomics Christopher Cassa, …
Staff
Kris Wetterstrand is the scientific liaison to the Director for Extramural Activities at the National Human Genome Research Institute.
… Genome Project, the ENCODE Project, an effort to identify functional DNA elements in the human genome, and the Human Microbiome …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… in cells from other lineages. NHGRI’s ENCyclopedia Of DNA Elements (ENCODE) Project was developed to identify all functional elements in the human genome, including epigenetic … LA, Garrett LJ, Elnitski L, Gallagher PG, Bodine DM. Functional analysis of a novel cis-acting regulatory region …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… Expression Project (GTEx) and the Encyclopedia of DNA Elements (ENCODE). GTEx is creating a catalog of human gene …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in September 2020.
… Description Podcast Series Registration 15 Next Steps for Functional Genomics NASEM Report 16 Heritable Human Genome … Technology Development Meeting 20 ENCyclopedia Of DNA Elements (ENCODE) ENCODE Program Website ENCODE Portal ENCODE … Site ENCODE Participants Search Candidate cis-Regulatory Elements by ENCODE (SCREEN) 21 Impact of Genomic Variation on …
Research Funding
The N​on-Coding Variants Program explores which variants in a region associated with a disease or trait cause the higher risk for the disease or trait
… or trait. However, most variants, including most of the functional ones that contribute to disease risk, are not in protein-coding regions. These functional variants generally affect the regulation of genes … Georgia Institute of Technology eQTL mega-analysis for functional assessment of multi-enhancer gene regulation R01 …
Policies and Guidance
For FY22, NHGRI’s extramural program will be operating under the NHGRI 2020 Strategic Vision.
… studies focused on the structure and biology of genomes; functional genomics; the genomics of disease; the … studies focused on the structure and biology of genomes; functional genomics; the genomics of disease; the …