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The Genomics Landscape
In the January 2024 issue of The Genomics Landscape, NHGRI Director Eric Green announces the appointment of Dr. Adam Phillippy as the founding director of the Center for Genomics and Data Science Research (CGDSR).
… technologies improve, new methods are required to make large-scale genomic edits. Such technologies would be particularly … entitled Genomic Medicine XV: Genomics and Population Screening . The meeting discussed the current state of …
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… HapMap, Human Genome Project … Population genomics is the large-scale application of genomic technologies to study …
The Genomics Landscape
In the February 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the December 2021 NHGRI symposium's success in confronting the difficult pasts of eugenics and scientific racism.
… analyses on them there lowers the barrier to performing large-scale computational research by eliminating the need to … and reproduction, disability, LGBTQ+ individuals, genetic screening, social and behavior genomics, and legacies of …
Policies and Guidance
A webpage with information and associated FAQs that describe various expectations for data sharing that are specific to NHGRI-supported studies.
… Studies  Study registration in dbGaP is required for large-scale human genomic studies, including those submitting data … vulnerable or marginalized groups. NHGRI recognizes that methods for de-identification of qualitative and other data …
Event
On November 16-17, 2023, the National Human Genome Institute will co-sponsor a workshop, Advances in the Genetic Architecture of Complex Human Traits, to take a historically grounded and forward-looking approach towards dissecting the genetic architecture of complex traits in humans.
… traits?  Advances in sequencing technologies and optical methods allow us to profile the molecular features of cells at scale. What’s needed, technically or theoretically, for … variables in genetic studies?  There are currently large efforts to diversify the demographics of genetic …
Research at NHGRI
The Division of Intramural Research conducts scientific studies in NHGRI's labs on and around the NIH campus in Bethesda, Md.
… greater understanding of human disease and develop better methods for detection, prevention and treatment of heritable … and application of DNA microarray technologies for large-scale analyses of gene expression; creation of innovative …
The Genomics Landscape
In the June 2, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new and improved Talking Glossary of Genomic and Genetic Terms - one of the premier educational resources offered by NHGRI, and it aims to help users better understand the basics of genomics and genetics.
… to identify genomic variants associated with phenotypes in large-scale sequence datasets. NIH is increasingly hosting … reconstruction to the present Does genetic and genomic screening keep open the door to eugenics? Funding …
Fact Sheets
DNA sequencing determines the order of the four chemical building blocks - called "bases" - that make up the DNA molecule.
… over and over again. … Researchers now are able to compare large stretches of DNA - 1 million bases or more - from … rare diseases. Other researchers are studying its use in screening newborns for disease and disease risk. Moreover, … of gene regulation in disease. Ongoing and planned large-scale projects use DNA sequencing to examine the development …
Staff
Dr. Shawn Burgess is the co-deputy director of NHGRI's Intramural Research Program.
… Institute of Technology, where he was part of a large effort to develop insertional mutagenesis in zebrafish, … In previous work, Dr. Burgess participated in a large-scale genetic screen for embryonic lethal phenotypes in the … over which genes are inactivated. As a result, targeted screening in a vertebrate is now possible for the first time, …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… technology currently being worked on in genomics including large-scale genetic sequencing, gene editing, artificial …