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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Talking Glossary
A gamete is a reproductive cell of an animal or plant.
… or plant. In animals, female gametes are called ova or egg cells, and male gametes are called sperm. Ova and sperm are haploid cells, with each cell carrying only one copy of each …
Educational Resources
Bacteria are small single-celled organisms.
… and in fact is estimated to contain more bacterial cells than human cells. Most bacteria in the body are harmless, and some are …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
… of DNA and other molecules that may be retained as cells divide to make more cells. … Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. When found in DNA, …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… and cellular dataset to help scientists understand how cells respond to specific biological and environmental … LINCS program generated dataset to help understand how cells functio … NHGRI and NCI award $33 million to improve … LINCS program generated dataset to help understand how cells function … In the July 2021 issue of The Genomics …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… aims to identify all functional elements in the human and mouse genomes. The project recently reported the findings … elements that may regulate the genes in the human and mouse genomes. Much of the work focused on DNA regions called … coronavirus vaccine Seeing coronavirus replicate in kidney cells NIH launches clinical trials network to test COVID-19 …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… structures located inside the nucleus of animal and plant cells. … Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single … packaging, DNA molecules would be too long to fit inside cells. For example, if all of the DNA molecules in a single …
Educational Resources
Haploid is the quality of a cell or organism having a single set of chromosomes.
… presence of a single set of chromosomes in an organism’s cells. Sexually reproducing organisms are diploid (having two … one from each parent). In humans, only the egg and sperm cells are haploid. … Haploid is the quality of a cell or …
Educational Resources
Monosomy refers to the condition in which only one chromosome from a pair is present in cells rather than the two copies usually found in diploid cells.
… pair instead of the usual two copies found in diploid cells. … Monosomy, Chromosome, Diploid, Genetic Diseasem, … in which only one chromosome from a pair is present in cells rather than the two copies usually found in diploid cells. When cells have one chromosome from a pair plus a …
Educational Resources
The instructions in a gene that tell the cell how to make a specific protein.