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Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense is the non-coding DNA strand of a gene. … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for … Antisense is the non-coding DNA strand of a gene. …
News Release
CMG investigators have made significant inroads in discovering genes underlying Mendelian conditions and have uncovered 470 new, previously unknown conditions.
… inherited, and typically caused by a mutation in a single gene. So far, researchers have identified the genomic causes … the program's progress and the breadth of Mendelian gene discovery to date. The authors also ruminated on the … disease. "Knowing that there is a relationship between a gene and a disease has enabled us to probe the development …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… to identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that … to turn genes on or off, or tune the exact levels of gene activity, help drive the formation of distinct cell … has benefited from and built upon decades of research on gene regulation performed by independent researchers around …
Talking Glossary
LOH (short for “loss of heterozygosity”) refers to a type of mutation that results in the loss of one copy of a segment of DNA (typically containing a gene or group of genes).
… of one copy of a segment of DNA (typically containing a gene or group of genes). … of one copy of a segment of DNA (typically containing a gene or group of genes). For most parts of the genome, human … of one copy of a segment of DNA (typically containing a gene or group of genes). …
Educational Resources
Dominant refers to the relationship between two versions of a gene.
… refers to the relationship between two versions of a gene. … refers to the relationship between two versions of a gene. Individuals receive two versions of each gene, known as alleles, from each parent. If the alleles of a … refers to the relationship between two versions of a gene. …
Educational Resources
Genomic variation refers to diversity in gene frequencies.
… Genomic variation refers to diversity in gene frequencies. … Genomic variation refers to diversity in gene frequencies. …
Talking Glossary
Intergenic regions are the stretches of DNA located between genes.
News Release
Doctors and researchers reunite with patient who received gene therapy for GM1 gangliosidosis.
… Doctors and researchers reunite with patient who received gene therapy for GM1 gangliosidosis. … after Jojo attended the last tea party, she received gene therapy for her rare disorder, GM1 gangliosidosis. … disorder caused by alterations in the DNA of a single gene, the GLB1 gene. The GLB1 gene makes an important enzyme …
News Release
Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
… between diabetes and previously unlinked ZRANB3 gene. … confirmed known genomic variants and identified a novel gene ZRANB3 , which may influence susceptibility to the disease in sub-Saharan African populations. The gene could also influence the development of T2D in other …
News Release
Genomic analyses turned up genes that belong to inflammatory pathways.
… They found that Rohith had a mutation in both copies of a gene involved in a process that affects protein function …