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The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… The NIH Intramural Sequencing Center (NISC) sits on the top floor of a research … houses the Center's state-of-the-art, high-throughput DNA sequencing facility. In a rather modest start in 1997 … leadership of its Founding Director Eric Green, NISC began DNA sequencing with six ABI 377 instruments in lab space …
News Release
Scientists have published the first complete, gapless sequence of a human genome, two decades after the Human Genome Project produced the first draft human genome sequence.
… of the roughly 3 billion bases (or “letters”) in our DNA is critical for understanding the full spectrum of human … achievement, providing the first comprehensive view of our DNA blueprint,” said Eric Green, M.D., Ph.D., director of … will empower genetic studies of human disease. The full sequencing builds upon the work of the Human Genome Project , …
The Genomics Landscape
In the April 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 15th anniversary of National DNA Day and the '15 for 15' Celebration.
… community will celebrate a yearly highlight - National DNA Day. On this day, students, teachers, and the public are … lives and what the future holds. This year's National DNA Day features an exciting assortment of online and … is the first topic, which was revealed today: DNA Sequencing. Advances in DNA sequencing technologies have …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
… DNA Sequence, Cancer, PCR, Polymerase Chain Reaction, …
Clinical Research
This team-based clinical service is provided by NHGRI to Intramural Investigators employing exome/genome sequencing.
… NHGRI to Intramural Investigators employing exome/genome sequencing to accomplish their research goals. The SGFS will … NHGRI to Intramural Investigators employing exome/genome sequencing. … DNA Sequencing, Exam Sequencing, Genome Sequencing, Secondary … NHGRI to Intramural Investigators employing exome/genome sequencing. …
News Release
Researchers sequence the genomes of healthy participants, then analyze the data to find presumed, mutations that might lead to a genetic condition.
… and bioinformatic challenges facing individualized genome sequencing in a clinical research setting. Once they … They have only recently been able to address it as DNA sequencing costs have plummeted. At this rate, just above … of how these mutations affect health. "We want to add DNA sequencing to the physician's toolbox," Dr. Biesecker …
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… A plasmid is a small, often circular DNA molecule found in bacteria and other cells. … Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA Sequencing, Genetic Engineering Recombinant DNA (rDNA) … A plasmid is a small circular DNA molecule found in bacteria and some other microscopic …
Event
NHGRI commemorates the life and legacy of genomics champion Representative Louise M. Slaughter (D-N.Y.), who passed away in March 2018, by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in her honor.
… in the House of Representatives that created National DNA Day, which celebrates the completion of the Human Genome Project and the anniversary of the discovery of DNA's iconic structure, the double helix. As one of the … passed away in March 2018 - by naming an annual National DNA Day lecture at the National Institutes of Health (NIH) in …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… , scientists have set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how … that make the genome work. Chemical tags that stick to the DNA impact chromatin organization and which genes are …
Research Funding
NSIGHT explores the implications, challenges and opportunities with the use of genomic sequence information in the newborn period.
… identifiable via newborn screening through promising new DNA-based analysis. Research related to the ethical, legal … (ELSI) of the possible implementation of genomic sequencing of newborns. Each research project collects a … currently screened for in newborns, how can genomic sequencing replicate or augment known newborn screenig …