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The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… then a postdoctoral research fellow in the laboratory of genomics pioneer Maynard Olson at Washington University … a set of studies describing how DNA variation can alter gene expression. The group of papers, published in Science …
News Release
American Indians and Alaska Natives IRB training programs at NIH ensure the welfare of people participating in federally regulated research.
… Mjoseth … Aha moments were among the unexpected outcomes of the Institutional Review Board (IRB) training program for … after Dr. Hull participated in the annual Short Course in Genomics provided by NHGRI's Education and Community … and high school science teachers learn ways to incorporate genomics content into their classrooms. "We had already …
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… Eric Green, M.D., Ph.D. … As is likely the case for many of your organizations, NHGRI and NIH are starting to bring … past few months, NHGRI staff will continue pursuing our genomics-driven mission, whether working remotely from home … one that covered about 99 percent of the genome's gene-containing regions and had an accuracy of 99.99 percent. …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Disease … A complex disease is caused by the interaction of multiple genes and environmental factors. … Genes, Cancer, Heart Disease, Gene-environment Interactions … A complex disease (or condition), when discussed in the context of genetics, reflects a disorder that results from the …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… decades, but the conversation about the science and ethics of genome editing has grown louder due to faster, cheaper, … will aid the development of new treatments, including gene therapy . … Scientists have had the knowledge and … creating targeted mutations to the genome. 5  Large-scale genomics projects that once took many years and tens of …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… The first such AGBT meeting was held in 2000, when most of the attendees were – in one way or another – busily … is gratifying to reflect on the amazing metamorphosis of genomics over the last two decades, especially with respect … link higher maternal blood pressure to placental gene changes Genetic profile may predict chance of type 2 …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… A transcriptome is a collection of all the gene readouts present in a cell. … The human genome is made up of DNA (deoxyribonucleic acid), a long, winding molecule that …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… This list of websites provide tools and resources for teaching the … of transcription and translation, two key steps in gene expression . … Transcription is the process of making an … Lesson Plan, Genomic Lesson Plan, Genetics Curriculum, Genomics Curriculm … Tools and resources for teaching the …
News Release
NHGRI researchers have discovered clues to the possible cause of recurring, non-contagious fevers and sores that affect only children. Several genes have been implicated with the syndrome, known as PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis), which could lead to new treatments.
… the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, have discovered clues … researchers have long thought that answers may lie in genomics. After ruling out the possibility that the syndrome is caused by mutations in a single gene, they considered the possibility that multiple genes are …
Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, Personalized Medicine, Gene Variant … A … trait. The method involves surveying the genomes of many people, looking for genomic variants that occur more …