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Binta Jalloh is a postdoctoral fellow at the Center for Research on Genomics and Global Health (CRGGH).
… Cancer Institute’s Laboratory of Receptor Biology and Gene Expression doing single molecule tracking to understand the … of transcription factors important for regulating gene expression in live budding yeast. Her primary role in the … under Dr. Quinn Vega studying signal transduction and gene expression using bacterial cells. Prior to coming to the USA, …
The Genomics Landscape
In the January 2024 issue of The Genomics Landscape, NHGRI Director Eric Green announces the appointment of Dr. Adam Phillippy as the founding director of the Center for Genomics and Data Science Research (CGDSR).
… the cellular receptor for SARS-CoV-2. In the edited mice, expression patterns of ACE2 were similar to those in humans …
Research Funding
Expired Funding Opportunity Announcements dating back to 1994, including Requests for Application, Program Announcements and Notices.
… Optional)" RFA-HG-21-026 : Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project (U24 Clinical Trials Not …
News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… However, they also uncovered many DNA variations and gene expression patterns that are not shared, potentially limiting … researchers found that differences appeared in specific tissue and cell types. "We didn't know before these results … sites (which identify regulatory DNA) in 45 mouse cell and tissue types to those in humans. They reported in Science …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … University of Massachusetts Medical School Rules Of Gene Expression Modeled On Human Dendritic Cell Response To …
News Release
NHGRI awards $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate.
… lead to imprecise and incomplete read-outs of gene expression and transcript diversity. Additionally, this way … than the genome in certain cases," he said. "Gene expression in a cancer cell is going to be different than in …
File
… Slides_Epigenetic effects and gene expression.pptx …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… facilitates cell growth and division, and the increased expression of JAK2 may inappropriately activate cell growth. … PD-L2, which suppress immune responses; their increased expression may help tumors escape destruction by the immune … process of adding methyl groups to DNA, which reduces gene expression. Hypermethylation occurs when this mechanism …
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
… genomic and social determinants; their effects on gene expression; as well as their contribution to health … cardiovascular disease morbidity and mortality and on gene expression among disproportionately affected subpopulations. …
Staff
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… modeling studies demonstrated that neuronal-targeted expression of NPC1 rescued neurodegenerative disease, … arrest and senescence, suggesting maintenance of SOX10 expression is important for melanoma progression. These … also evaluate the effects these gene mutants have on other tissue types. Together, these studies will increase …