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News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… affected by faulty gene regulation, such as cancer, diabetes and Parkinson's disease. NHGRI launched the Genomics …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… research was also supported by the National Institute of Diabetes and Digestive and Kidney Diseases, the National …
For Patients and Families
​Clinical research is research conducted with human subjects, or material of human origin, in which the researcher directly interacts with human subjects.
… the genetic components of common disorders such as cancer, diabetes, and heart disease, as well as less common …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… diseases with a genomic basis, like cystic fibrosis and diabetes. There are two different categories of gene …
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… humans, such as various forms cancers, infections and even diabetes. In addition, a vast number of regions within the …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… Ghana, Kenya and Nigeria as part of the Africa America Diabetes Mellitus study.  Charles Rotimi, Ph.D., scientific …
News Release
NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.
… numerous conditions, such as coronary heart disease and diabetes, and to identify people who are at high risk. This …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… a pathway, the result can be a disease such as cancer or diabetes. … There are many types of biological pathways. …
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
… may help Valium calm nerves Nicotine addiction linked to diabetes through a DNA-regulating gene in animal models One …
File
… AAA, extreme obesity and related conditions, remission of diabetes after bariatric surgery Group Health, University of … 67.7% EA, 19.7% AA, 4.8% Asian 4,987 (83% female) Type 2 diabetes, diverticulosis, lower GI non-syndromic polyp, …