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About NHGRI

Answers to frequently asked questions on how the NHGRI receives and uses its funding.

… receives its funding. For more information on the budget process, visit the House of Representatives website … in these areas. All applications undergo a two-tier, peer-review process. NHGRI funds the proposals that are ranked …

Policies and Guidance

FY2023 NHGRI Funding Policy

For FY2023, NHGRI’s extramural program will be operating under the NHGRI 2020 Strategic Vision.

… of science, are particularly high-risk projects, or when review or Council recommend a shorter duration. Applicants … (RPG) and Center applications, beyond those recommended by peer review, will be handled on a case-by-case basis. … a meritorious grant application, how the peer review process works, and how to work within the NIH system. … NHGRI …

Research Training

NHGRI Fellowships FAQ

Answers to Frequently Asked Questions for Ruth L. Kirschstein Individual National Research Service Award (NRSA) Fellowships with awards specifically for predoctoral students.

… Management Specialist for the fellowship. What is the process for changing mentors? Transitioning to a new mentor … research project stays within the scope of the original, peer-reviewed proposal. An official request should be … the research project will continue to meet the original peer-reviewed proposal, and a current biosketch for the new …

AnVIL

DUOS

The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.

… retains oversight by the NIH DACs while enabling efficient review and approval of data access requests (DARs). The D … burden on signing officials and the decrease the review and approval times of researcher DARs. … National … between DUOS semi-automated representation of the DAC process and the fully human review remained high (95%), and …

Staff

William M. Klein, Ph.D.

Dr. Klein is an Adjunct Investigator in NHGRI’s Center for Precision Health Research, where he collaborates on several projects involving genetic risk communication

… decisions. Dr. Klein's work has appeared in over 200 peer-reviewed articles and has been supported by NCI, the …

Policy Issues

Informed Consent

Informed consent shows respect for personal autonomy and is an important ethical requirement in research.

… In designing an effective informed consent process for genomics research, researchers should consider … laws, biobanks and data repositories, or Institutional Review Boards (IRBs). The informed consent process should be a dynamic interaction between researchers, …

The Genomics Landscape

Artificial intelligence and machine learning becoming pervasive at NHGRI and in genomics

In the January 5, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how artificial intelligence and machine learning are becoming omnipresent throughout NHGRI and in genomics.

… to differences in how people metabolize (e.g., chemically process) innate and foreign substances. In some cases, these … 37 data resources found by an international peer-review panel to be critical for the worldwide life science …

Funding Opportunities

Funding for New and Early Stage Investigators

Funding for New and Early-Stage Investigators

… how a program officer can help you throughout the process. View the recorded seminar NIH Grants Process: A … of Extramural Research and the Center for Scientific review hosted a webinar that walks through essential aspects … (NOFOs), an overview of the grants process and peer review, NIH and applicant institution …

Research Funding

Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium

Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.

… disseminated to PRIMED and the broader community through peer-reviewed publications where appropriate. Data Analysis … for use in PRIMED. This will occur through literature review, input from internal and external investigators with …

Secondary Genomics Finding Service

Clinical Research Staff and Protocol Coordinators

… How does it work? … 1. Review of data We will review your de-identified sequencing data to look for … for confirmation testing. SGFS staff can help with this process. “Exome-Confirmation, Saliva, NHGRI” …