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A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… replacing it or disrupting it with an artificial piece of DNA. … Knocking out the activity of a gene provides valuable … researchers use one of two methods to insert artificial DNA into the chromosomes contained in the nuclei of ES cells. … this is done by introducing an artificial piece of DNA that shares identical, or homologous, sequence to the …
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Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… in some cases, more comprehensively analyze and interpret DNA sequence information from cancer patients. They have … different tumor sample storage methods produced comparable DNA sequencing information - an important step that may … accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients. … Cancer DNA …
Educational Resources
Transgenic means that one or more DNA sequences from another species have been introduced by artificial means.
… Transgenic … Transgenic means that one or more DNA sequences from another species have been introduced by … artificial means. … Cell, Cloning, Deoxyribonucleic Acid (DNA), Gene, Germ Line … Transgenic refers to an organism or … been altered by the introduction of one or more foreign DNA sequences from another species by artificial means. …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also … specific signature results from a chemical modification of DNA called methylation, which can control the expression of … genes like a dimmer on a light switch. … Higher amounts of DNA methylation (hypermethylation), like that found by the …
Educational Resources
A nucleotide is the basic building block of nucleic acids. RNA and DNA are polymers made of long chains of nucleotides.
… is the basic building block of nucleic acids. RNA and DNA are polymers made of long chains of nucleotides. … ACGT, … Acid, Base Pair, Genetic Code, Deoxyribonucleic Acid (DNA), Ribonucleic Acid (RNA) … A nucleotide is the basic building block of nucleic acids (RNA and DNA). A nucleotide consists of a sugar molecule (either …
Educational Resources
Restriction fragment length polymorphism (RFLP) is a type of polymorphism that results from variation in the DNA sequence recognized by restriction enzymes.
… a type of polymorphism that results from variation in the DNA sequence recognized by restriction enzymes. … Deoxyribonucleic Acid (DNA), Electrophoresis, Genetic Marker, Polymorphism, … to differences (or variations) among people in their DNA sequences at sites recognized by restriction enzymes. …
Educational Resources
Ancestry-informative markers are sets of polymorphisms for a DNA sequence found in different frequencies between populations from different geographical regions.
… markers are sets of polymorphisms for a DNA sequence found in different frequencies between … … Ancestry, Genome, Family Health History, Genotype, DNA Sequence … Ancestry-informative markers are sets of polymorphisms for a particular DNA sequence that appear in substantially different …
News Release
NIH expands its Encyclopedia of DNA Elements Project, which is creating a fundamental genomics resource scientists to study human health and disease.
… of Health (NIH) plans to expand its Encyclopedia of DNA Elements (ENCODE) Project, which is generating a … aim to pinpoint the genomic locations of genes and the regulatory elements that control them. With these new awards, … then can put two parts of the genome - a gene and its regulatory element, for example - in close contact. Having a …
Educational Resources
An open reading frame is a portion of a DNA molecule that, when translated into amino acids, contains no stop codons.
… Reading Frame … An open reading frame is a portion of a DNA molecule that, when translated into amino acids, contains … Amino Acids, Base Pair, Codon, Deoxyribonucleic Acid (DNA) … An open reading frame, as related to genomics, is a portion of a DNA sequence that does not include a stop codon (which …
Educational Resources
ACGT is an acronym for the four types of bases found in a DNA molecule: adenine (A), cytosine (C), guanine (G), and thymine (T).
… ACGT is an acronym for the four types of bases found in a DNA molecule: adenine (A), cytosine (C), guanine (G), and … Thymine, Cytosine, Base Pair, Gene, Deoxyribonucleic Acid (DNA), Ribosome … ACGT is an acronym for the four types of bases found in a DNA molecule: adenine (A), cytosine (C), guanine (G), and …