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Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… resource for defining the biological significance of ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working … between the distinct genomic variation characteristic of African-Americans (AA) and the exposome of social …
Educational Resources
Ancestry-informative markers are sets of polymorphisms for a DNA sequence found in different frequencies between populations from different geographical regions.
… Ancestry-informative Markers … Ancestry-informative markers are sets of polymorphisms for a … between populations from different geographical regions. … Ancestry, Genome, Family Health History, Genotype, DNA …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… underpinnings of obesity in continental Africans and African Americans. They discovered that approximately 1 percent of West Africans, African Americans and others of African ancestry carry a genomic variant that increases their risk of …
Talking Glossary
Local ancestry refers to segments of an individual’s genome that can be traced back to ancestors from different populations living in different places and at different times.
… Local Ancestry … Local ancestry refers to segments of an individual’s genome that … living in different places and at different times. … Local ancestry refers to segments of an individual’s genome that … called haplotypes . In the genome of a person with ancestry recently derived from people in many regions of the …
News Release
Genomic variants that increase risk of kidney disease are found in nearly one-third of West Africans
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people of West African ancestry.
… for earlier health interventions for people with West African ancestry. … A study from researchers at National Institutes … the risk of developing chronic kidney disease among African Americans. However, not much is known about how these …
15 Ways Genomics Influences Our World
Genomics is illuminating human and family origins at a level not previously possible.
… way to decipher the various stories of human origins and ancestry. … Nearly 20 years ago, scientists developed … Carlos Bustamante's research groups showed in 2010 , an African American individual in the United States has, on average, about 75-80 percent West African ancestry and about 20-25 percent European ancestry. …
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of African ancestry with these genetic mutations have a higher risk of …
Talking Glossary
Understand the terms and concepts used in genetic research
… Genetic Ancestry … Genetic ancestry refers to information about the people that an … from, including their genetic relationships. … Genetic ancestry refers to information about the people that an …
News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… clues to medical conditions in people of sub-Saharan African ancestry, and indicates that the migration from Africa in the … data to explore the genomic-variation landscape of several African ethno-linguistic groups. A genotype is a subset of a …