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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Educational Resources
A stem cell is a cell with the potential to form many of the different cell types found in the body.
… Stem Cell … A stem cell is a cell with the potential to form … of the different cell types found in the body. When stem cells divide, they can form more stem cells or other cells … have the potential to form a complete individual, whereas adult stem cells can only form certain types of specialized …
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… called Hydractinia, does so because it produces germ cells, which are precursors to eggs and sperm, nonstop … Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… Ph.D., developed the breakthrough technique to return any adult cell to its earliest stage of development (a pluripotent stem cell) and change it into different types of cells in the body. … Called induced pluripotent stem cells …
News Release
A new study examines why some people grow out of childhood attention deficit hyperactivity disorder (ADHD), while others continue to have symptoms as adults.
… remission. The researchers looked at brain function in 205 adult participants: 101 participants had been diagnosed with … mapping of the brain's functional connectivity and the adult outcome of attention deficit hyperactivity disorder . … 2017. … Why Some People Outgrow ADHD … Related Content … Adult ADHD: An imbalance between the online and offline brain …
For Patients and Families
An adult has an "undiagnosed condition" when a physician is unable to find a diagnosis for certain characteristics or symptoms.
… An adult has an "undiagnosed condition" when a physician is … counselors be helpful? … An Undiagnosed Condition in an Adult FAQ … An adult has an "undiagnosed condition" when a physician is …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… These and other symptoms result when mutated red blood cells take a sickle shape, blocking blood flow and decreasing … to improve our understanding of the disease." Normal blood cells (left) and the blood cells in Sickle cell disease, which do not flow through the …
Educational Resources
A somatic cell is any cell of the body except sperm and egg cells.
… Somatic Cells … A somatic cell is any cell of the body except sperm and egg cells. … Cell, Chromosome, Diploid, Mutation, Germ Line … Somatic cells are the cells in the body other than sperm and egg …
Educational Resources
A cell cycle is a series of events that takes place in a cell as it grows and divides.
… mitosis, and completes its division. The resulting cells, known as daughter cells, each enter their own interphase and begin a new round …
News Release
Scientists set their sights on chromatin - the DNA-protein complex that packages DNA into chromosomes in the cell - to better understand how the genome works.
… its make-up is different among cell types, even among cells that are similar. Investigators from two National Human … what to do - among three types of cells: mouse embryonic stem (ES) cells, embryonic fibroblasts and hematopoietic … subtypes based on chromatin make-up. They found that each stem cell subtype had a different ability to develop into …