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A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… Locus … A locus is the specific physical location of a gene or other … sequence on a chromosome, like a genetic street address. … Locus, Allele, DNA Polymorphism, Gene, Chromosome … A locus, as related to genomics, is a physical site or location …
Educational Resources
A trait is a specific characteristic of an organism.
… Trait … A trait is a specific characteristic of an organism. … Gene, Gene Expression, Phenotype, Genotype … A trait, as related to … of both. Traits can be qualitative (such as eye color) or quantitative (such as height or blood pressure). A given …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… documenting the stretches of human DNA that influence gene expression - a key way in which a person's genome gives rise to an observable trait, like hair color or disease risk. This atlas is a … the project. Sections of the genome, known as expression Quantitative Trait Loci (eQTL) work to control how genes are …
Research Funding
Building upon a foundation of quantitative genetics laid over a century ago, applying modern genomic approaches to resolve how genetic and non-genetic factors shape variation in human diseases and traits.
… goal of human genetics is to decompose the sources of trait variation into constituent causal factors. The hope is … or influence those traits. Although the foundation of quantitative genetics was laid over a century ago, there … … Program Staff … Building upon a foundation of quantitative genetics laid over a century ago, applying …
Talking Glossary
Dominant, as related to genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait.
… genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait. … Dominant, as related to genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and … GTEx investigators used a methodology - expression quantitative trait locus (eQTL) analysis - to gauge how variants affect …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… has awarded eight grants as part of the Genotype-Tissue Expression (GTEx) project to explore how human genes are … the role that genomic variation plays in modulating that expression. … An Atlas of Human Gene Expression The GTEx awards will contribute to a resource …
Educational Resources
A polygenic trait is one whose phenotype is influenced by more than one gene.
… Polygenic Trait … A polygenic trait is one whose phenotype is influenced by more than one … Inheritance, Phenotype, Complex Disease … A polygenic trait is a characteristic, such as height or skin color, that …
Educational Resources
Recessive Traits and Alleles is a quality found in the relationship between two versions of a gene.
… genetics, refers to the relationship between an observed trait and the two inherited versions of a gene related to that trait. Individuals inherit two versions of each gene, known … as alleles, from each parent. In the case of a recessive trait, the alleles of the trait-causing gene are the same, …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… Gene Expression … Gene expression is the process by which the information encoded in … Code, DNA, DNA Sequence, Proteins, Base Pairs … Gene expression is the process by which the information encoded in …