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- Ethical, Legal and Social Implications (ELSI) Research Program2
- Genetic Architecture of Complex Traits1
- Genome Technology Program4
- Impact of Genomic Variation on Function (IGVF) Consortium1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
Educational Resources
Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism.
… to the production of cancer therapies, brewing yeasts, genetically modified plants and livestock, and more. … …
Outreach
The USA Science and Engineering Festival is an opportunity to take part in hands-on genetics and genomics activities.
Jobs at NHGRI
NHGRI is seeking a postdoc to join the Systems Biology and Genome Engineering Section in Bethesda, Maryland.
News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
… growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in … in their mitochondria, specifically in the liver. The MMA mice also allowed them to study the response to … News Feature: Elevated hormone flags liver problems in mice with methylmalonic acidemia (MMA) … Researchers have …
News Release
NHGRI-funded researchers to be honored with Presidential Early Career Awards for Scientists and Engineers
Staff
Lisa Garrett is an associate investigator and director of the NHGRI Transgenic Mouse Core.
… at NCI, Frederick, Maryland. generating transgenic mice for models of cancer. At this time, she started her … core website along with other useful information for using genetically engineered mice in research. Most recently, Ms. Garrett …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… a child's risk of death from infectious diseases. Yeast engineered to produce rose oil as an eco-friendly and …
News Release
NHGRI researchers are studying the link between Parkinson's disease, and a rare disorder, Gaucher disease, by cross-breeding mice with the disease mutations.
… and a rare disorder, Gaucher disease, by cross-breeding mice to carry human mutations causing each of the two … extra copies of a mutated form of alpha-synuclein. These mice were then mated with mice missing a copy of the GBA1 gene. The resulting mice - …
Talking Glossary
GMO (short for “genetically modified organism”) is a plant, animal or microbe in which one or more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the characteristics of an organism.
… Genetically Modified Organism (GMO) … GMO (short for “genetically modified organism”) is a plant, animal or microbe … the characteristics of an organism. … GMO (short for “genetically modified organism”) is a plant, animal or microbe …
Staff
Dr. Meru Sadhu is the head of the Systems Biology and Genome Engineering Section at the National Human Genome Research Institute.