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News Release
Researchers from NHGRI, Oxford University and other National Institutes of Health centers have developed and tested a new method to predict hospital-acquired infections involving five other important pathogens.
… either had a confirmed case or were suspected of having an infection — called co-presence — as a measure to predict … 24 hours in the presence of another patient suspected of infection with one of the five pathogens we studied,” said … 24 hours in the presence of another patient suspected of infection with one of the five pathogens we studied. The …
Clinical Research
An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home Participation).
… Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home … may be particularly at risk for decline associated with infection. The goal of this study is to compare biomarkers … to help develop therapies to reduce the severity of infection in people with mitochondrial disease. … Anyone with …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… M.D., assistant research physician in NHGRI’s Metabolism, Infection and Immunity Section and co-first author of the … M.B.B.Ch. , NHGRI investigator, head of the Metabolism, Infection and Immunity Section and senior author of the …
Clinical Research
A Longitudinal Natural History Study of Children with Mitochondrial Disease (at the NIH Clinical Center).
… The Metabolism, Infection and Immunity (MINI) Study is a longitudinal natural … Health (NIH) that aims to define the relationship between infection, immunity and clinical decline in individuals with … by problems with the cell’s ability to produce energy. Infection in individuals with mitochondrial disease can lead …
Clinical Research
The Metabolism, Infection and Immunity (MINI) Section aims to define the relationship between infection, immunity and clinical decline in individuals with mitochondrial disease.
… The Metabolism, Infection and Immunity (MINI) Section at the National … of Health (NIH) aims to define the relationship between infection, immunity and clinical decline in individuals with … by problems with the cell’s ability to produce energy. Infection in individuals with mitochondrial disease can lead …
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… period of time without being deadly. The lengthier the infection, the longer the virus has to adapt and spread to … disease or cancer, are more vulnerable to a severe viral infection. Some individuals also have specific genomic … including the relationship between the level of viral infection and specific genomic variants. … Yes. The human …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… clinical implications - in head and neck cancers caused by infection with the human papillomavirus (HPV). HPV is the … findings may provide more detailed explanations of how HPV infection and smoking play roles in head and neck cancer risk … should be able to prevent the cancers caused by HPV infection in head and neck cancers and elsewhere, including …
Genetic Disorders
Cystic fibrosis is a genetic disease that causes the body to produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas.
… produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas, which stops digestive … produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas. … Cystic Fibrosis, CF, … produce thick, sticky mucus that clogs the lungs, leads to infection, and blocks the pancreas. … Genetic Disorders …
Staff
Dr. Gordon-Lipkin is a researcher and child neurologist with expertise in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section.
… in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section, at NHGRI. She … longstanding research interests focus on the effects of infection and inflammation on brain development and … L, Hirano M, et al. Risk mitigation behaviors to prevent infection in the mitochondrial disease community during the …
Staff
Dr. Pamela Schwartzberg is a adjunct investigator in NHGRI's Genetic Disease Research Branch.
… Physicians (AAP). … The ability to successfully fight infection requires the coordinated activation of lymphocytes … by which lymphocytes mount effective responses to infection and immunization and to translate these findings to … of powerful reagents for examining lymphocyte responses to infection and immunization. However, the group has also …