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News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer. … More than 10,000 Tumors Analyzed "This project is the culmination of more than … with unprecedented understanding of how, where and why tumors arise in humans, enabling better informed clinical …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… examining the entire genomes of 50 of the 66 ChRCC tumors studied, a high number for a rare cancer. The study … DNA. This led researchers to discover that ChRCC tumors favor a different energy-generating process than that … in the mitochondria, the cell's energy supplier. … Kidney tumors, chromophobe renal cell carcinoma, ChRCC, The Cancer …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… the most common type of brain tumor in adults, but these tumors are difficult to treat. The research team noticed that … folded, causing genetic neighborhoods to merge. Within the tumors that have a mutated IDH gene, scientists found that …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… to explore therapies in defined sets of patients whose tumors have specific genomic abnormalities. Stomach cancers … complex statistical analyses of molecular data from 295 tumors. They used six molecular analysis platforms including … DNA sequencing, RNA sequencing, and protein arrays. Tumors in the first group, which represented 9 percent of the …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… head and neck cancers, noticeably in oropharyngeal tumors, has created an even greater sense of urgency in the … behind the mouth. "We're uncovering differences between tumors with and without HPV infection, and these new data are … the study, researchers performed genomic analyses on 279 tumors - head and neck squamous cell carcinomas (HNSCC) - …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… Reports First Results of Comprehensive Study of Brain Tumors  (2008)  The Cancer Genome Atlas Awards Funds for …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… (which is commonly affected in cancers) in 44 percent of tumors. TP53 makes the p53 tumor suppressor protein, which … identified potential drug targets in 69 percent of the tumors evaluated. They found frequent mutations in the ERBB2 … responsible for cervical cancer - was found in bladder tumors. This suggests that viral infection can contribute to …
News Release
The TCGA network describes uterine and bile duct cancer.
… uncontrolled cell growth that is the hallmark of malignant tumors. Last month, two publications from the TCGA network …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… identified, clinicians may be able to treat patients whose tumors have specific gene changes with drugs currently …
Event
On February 16, 2023, the National Human Genome Research Institute (NHGRI) held a follow-up working group consultation after the 14th Genomic Medicine meeting, Genomic Medicine XIV: Genomic Learning Healthcare Systems.