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News Release

Differences in our DNA have major influences on how our genomes function, but how?

Researchers from the NHGRI-funded Impact of Genomic Variation on Function Consortium are exploring how genomic variation affects genome function.

… test variants to determine which ones can affect gene expression in common human diseases. Hyejung Won, Ph.D. , an … — regions of the genome that can dampen or amplify the expression of genes, similar to how a dial on a radio turns … are using pancreatic cells in tiny, three-dimensional tissue cultures, known as organoids, to study how genomic …