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Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… product or a change in the cell. … Biochemistry, Gene Expression, Metabolism, Medication … A biological pathway is …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
… chromosome. … Histones, DNA, Chromatin, Double Helix, Gene Expression … A histone is a protein that provides structural … shape. Histones also play a role in the regulation of gene expression. … Educational Resources …
Educational Resources
Nucleic acids are large biomolecules that play essential roles in all cells and viruses.
… Nucleotide, Genetic Code, DNA, Deoxyribonucleic Acid, Gene Expression … Nucleic acids are large biomolecules that play … A major function of nucleic acids involves the storage and expression of genomic information. Deoxyribonucleic acid, or …
Educational Resources
Genomics refers to the study of the entire genome of an organism whereas genetics refers to the study of a particular gene.
… to the study of a particular gene. … Genomics, Genes, Gene Expression, Human Genome Project … Genomics is a field of …
News Release
NIH researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate.
… this is the first study to use postmortem human brain tissue to investigate ADHD. Other approaches to studying … specific genes are turned on or off, also known as gene expression . They studied two connected brain regions … studies are rare because of the limited donation of brain tissue but are incredibly valuable because they provide …
Educational Resources
An exon is the portion of a gene that codes for amino acids.
… that codes for amino acids. … Intron, DNA Sequence, DNA Expression, RNA, Genes, Genetic Code … An exon is a region of …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… respectively) that form a dimer for DNA binding and gene expression regulation, are frequent targets of such … Liu PP. Zebrafish homolog of the leukemia gene CBFB : its expression during embryogenesis and its relationship to scl … stem cells generated by non-integrating plasmid expression. Cell Stem Cell, 10:337-44. 2012. [ PubMed ] …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… … Cell, Deoxyribonucleic Acid (DNA), Enzyme, Gene Expression, Restriction Enzyme, Vector … Recombinant DNA …
Educational Resources
Non-coding DNA corresponds to the portions of an organism’s genome that do not code for amino acids, the building blocks of proteins.
… the building blocks of proteins. … DNA Sequence, Gene Expression, Chromosome, Non-coding DNA, Junk DNA, Genetic … serve functional roles, such as in the regulation of gene expression, while other areas of non-coding DNA have no known …
Educational Resources
Evolution is the process by which organisms change over time.
… over time. … Genetic Mutation, Genetic Variation, Gene Expression, Charles Darwin, The Origin Of Species, Genes … …