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Educational Resources
In biology, an organ (from the Latin "organum" meaning an instrument or tool) is a collection of tissues that structurally form a functional unit specialized to perform a particular function.
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… medical students are more likely to recommend observing kidney function and screening for diabetes in response to the … medical students were more likely to recommend monitoring kidney function when taking over-the-counter medication if …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… can experience excruciating pain all over their bodies, kidney problems, higher risk of stroke and in rare cases, …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… with these genetic mutations have a higher risk of kidney disease. … "Strides have been made but more research …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… that lead, specifically, to fast-growing and aggressive tumors. Formation or production of tumors-tumorigenesis-can result from genomic alterations that … Identifies somatic genomic alterations that drive sporadic tumors using whole-exome and whole-genome sequencing …
News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… They include pulmonary embolism , proteinuria and chronic kidney disease . Findings from this first comprehensive … risk for pulmonary embolism, proteinuria and chronic kidney disease. They also found a moderate level of evidence … results. "Our study did find that SCT is a risk factor for kidney disease, but there is insufficient evidence to show …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… (Herceptin). This therapy works only for women whose tumors have a particular genetic profile that leads to … ability to develop into every type of tissue (skin, liver, kidney, blood, etc.) found in an adult human. Adult stem …
Event
The Genomics and Health Disparities Lecture Series was formed to enhance opportunities for dialogue about how innovations in genomics research and technology can impact health disparities. Topics will range from basic science to translational research.
… National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute on Minority Health …
News Release
Investigators with The Cancer Genome Atlas have discovered genomic differences in head and neck cancers caused by infection with the human papillomavirus.
… head and neck cancers, noticeably in oropharyngeal tumors, has created an even greater sense of urgency in the … behind the mouth. "We're uncovering differences between tumors with and without HPV infection, and these new data are … the study, researchers performed genomic analyses on 279 tumors - head and neck squamous cell carcinomas (HNSCC) - …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… the utility of dogs for cancer genetics by mapping kidney cystadeno-carcinoma in German Shepherds, prior to its … of the bladder 27, 28 , and canine transmissible venereal tumors 29 . Prostate Cancer : We have worked for the last … landscape of BRCA2-associated aggressive prostate tumors, defining a signature of an increased somatic mutation …