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The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… on PBS’s “ Finding Your Roots .” This series explores the ancestry of people from diverse backgrounds, taking viewers … the loss of Ken Paigen Dr. Collins learns about his ancestry on PBS’ Finding Your Roots Seven questions for a …
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… population genomics research can be used to study human ancestry, migrations and health. … Population genomics is the …
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… an approach that oversimplifies the complex interplay of ancestry, health, disease and drug response. … In a May 26 …
Genomics 101
Find out how the rapidly emerging field of genomics is transforming our understanding of human health and enabling advances that benefit all of humankind.
… genome contains many important clues about you—from your ancestry to the way your body responds to diseases, …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
… … Polygenic scoring accuracy varies across the genetic ancestry continuum Ding et al. Nature . 2023 … that involve data generated from individuals of European ancestry, but such studies are limited in their applicability …
Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a patient's genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… on data obtained from people with predominantly European ancestry. This means that pharmacogenomic tests may miss …
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
… or fat-like substance in the blood) in people of African ancestry. The researchers investigated whether smoking … a concerted effort to include many people of non-European ancestry since there are too few genomics studies of diverse … of lipids in terms of number of participants with African ancestry. This enabled researchers to find new gene regions …
Research at NHGRI
CRGGH uses genomic tools to understand the pathobiology of metabolic disorders, including obesity, hypertension, diabetes, dyslipidemia, and kidney disease.
… Partial Test. Hum Hered, 73:73-83. 2012. [ PubMed ] Ancestry Shriner D, Tekola-Ayele F, Adeyemo A, Rotimi CN. … reconstruction of the 140,000 year history of modern human ancestry. Sci Rep 4:6055. 2014. [ PubMed ] Ancestry_2014.bed Ancestry_2014.bim Ancestry_2014.fam …
File
… Ancestry and Disease in the Age of Genomic Medicine (October …