Search Results
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… of gene regulatory elements and variants critical to complex cellular phenotypes HG012053 Mapping Awards Jason … cell models and genomic engineering, towards resolving the complex cell-type-specific and context-dependent interplay … last updated March 15, 2022. … Differences in our DNA have major influences on how our genomes function, but how? News …
The Genomics Landscape
In the March 2024 issue of The Genomics Landscape, NHGRI Director Eric Green spotlights the Centers of Excellence in Genomic Science (CEGS) Program evaluation.
… appointments of two people into leadership positions of major significance to NHGRI. First, later this spring, the … Technology (CIT). In this role, Sean will play a major part in helping to optimize NIH’s data ecosystem, … multidisciplinary groups of investigators and tackling major genomics challenges. The centers are required to …
Outreach
Five pieces from the Genome: Unlocking Life’s Code exhibition are now on display at the National Institutes of Health (NIH) campus in Bethesda, MD.
… health. Is Genetic Information Different? New and often-complex ethical and medical questions have emerged as genetic …
News Release
Celebrating 30 years of genomics that has transformed our understanding of life and improved health.
… to zoom. The Human Genome Project (HGP) Timeline contains major milestones in genomics from 1865 to 2003. Credit: … a catalog of human genes and beginning to understand the complex choreography involved in gene expression. The growing …
Research at NHGRI
The Division of Intramural Research conducts scientific studies in NHGRI's labs on and around the NIH campus in Bethesda, Md.
… Bayview campus in Baltimore, Maryland and the Twinbrook complex in Rockville, Maryland. The Division is led by the … a number of high-risk efforts to unearth clues about the complex genetic pathways involved in human diseases. These …
News Release
Researchers from NHGRI and the Undiagnosed Diseases Program (UDP) have discovered a new neurological condition characterized by issues with motor coordination and speech.
… in the cerebellum, the part of the brain involved in complex movement among other functions. Additionally, the … different genes, so changes in redundant genes can have major impacts in the brain,” said Malicdan. To simulate cells … different genes, so changes in redundant genes can have major impacts in the brain. Still, much about ATG4D remains …
Fact Sheet
Eugenics is the scientifically erroneous and immoral theory of “racial improvement” and “planned breeding,”
… inherited in a simple fashion. Similarly, they believed complex diseases and disorders were solely the outcome of … risk scores, that can estimate risks for more genetically complex disorders have raised concerns among ethicists that …
Event
NHGRI and the University at Buffalo Center for Disability Studies will hold a two-day symposium on October 6-7, 2022 to address historical constructions of disability and ableism, with a focus on the “irreducibility” of individuals with disability and the history of disability.
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… dosing medications, an approach that oversimplifies the complex interplay of ancestry, health, disease and drug …
About NHGRI
The Genomic Data Science Working Group facilitates engagement of the National Advisory Council for Human Genome Research on genomics and data science issues.
… the National Advisory Council for Human Genome Research on complex issues at the interface between genomics and data …