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News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… stage for the domestic dog to provide a highly relevant system in which to further develop BRAF -targeted therapy … served as a model in cancer research. They were central to immune system research that led to development of bone marrow …
News Release
Three research teams funded by NIH gather data at the most basic molecular levels about the biological processes that make up the human microbiome.
… production, protection against invading pathogens and immune system support. Now, the number of bacterial species living … and possibly trigger onset of disease linked to the immune system. Such stressors could particularly affect …
Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a patient's genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… some cases, pharmacogenomic testing can be used to predict immune reactions to certain medications. For example, people … the cancer cells from growing and signals the patient’s immune system to kill the cancer cells. Pharmacogenomic testing of a …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… Research NIH Researchers Link Graying Hair and the Immune System Essential Malaria Parasite Genes Revealed Genomic … NIH Study Finds Gut Microbiome Can Control Antitumor Immune Function in Liver One Patient's Diagnostic Odyssey …
Staff
Dr. Dan Kastner is an NIH Distinguished Investigator in Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch.
… of the evolutionarily ancient innate branch of the human immune system. Dr. Kastner has won a number of awards and honors, … autoinflammatory disease to denote a broad group of innate immune disorders. Based on other clinical encounters, the …
News Release
NIH will support research that incorporates DNA sequence information into electronic medical records.
… high neutrophil count can signal a disorder involving the immune system. They will use DNA sequencing to examine the genetic … are associated with cardiovascular, neuropsychiatric and immune-mediated conditions described in electronic medical …
Staff
Dr. Lanata is a staff clinician in NHGRI's Genomics of Autoimmune Rheumatic Disease Section.
… I, Jain TS, Nititham J, et al. Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… answered nearly a hundred questions about CRISPR, the immune system, and how CRISPR can be used to treat specific … Innovative Genomics Institute. The recent finding of human immune responses to CRISPR-Cas9 proteins in human cells is an …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… network models, taking advantage of the dynamics of the system as the cells transition from one physiologic state to … PI(s) Institution Study Title (RePORTER Link) Biological System Alexander Hoffmann, Ph.D. and Douglas Black, Ph.D. … Angeles "Ribonomics" Of Gene Regulation To Predict Innate Immune Responses Post-transcriptional response to pathogens, …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
… practices. … Genomics Research Researchers find weaker immune response to viral infections in children with …