Search Results
Healthcare Provider Genomics Education Resource
Genomics plays a role in every area of nursing, whether nurses are at the bedside providing one-on-one care, treating entire populations, teaching the next generation of nurses, or making discoveries in the lab.
… scale changes such as duplications or deletions. Gene expression tests analyze mRNA and can identify over- or under-expression of certain genes, which affects what proteins are …
Event
On November 1-5, 2023, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.  The annual meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics.Â
… M Buckley eQTL analysis of canine testes identifies gene expression patterns associated with canine body size. PB1092 … Sequencing to Fine-Map an Alloimmunization Susceptibility Locus in Sickle Cell Disease PB3447 Vence Bonham …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… and transcriptomic technologies alongside population and quantitative genetics to identify the genes and gene-pathways … in the response to red blood cell transfusions and the expression of beta-globin genes.   … We are a part of a … Disease Reveals African-Ancestry-Limited Association at a locus on Chromosome 5. Blood Adv. 2018 Dec 26;2(24):3637-364; …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… H, Charles BA, Christman MF, Rotimi CN. UGT1A1 is a major locus influencing bilirubin levels in African Americans. Eur … Y, Oli J, Johnson T. Genomewide scan and fine mapping of quantitative trait loci for intraocular pressure on 5q and 14q in West …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… in humans often fail due to sample size limitations and locus heterogeneity; factors the Ostrander lab argues can … metastatic lethal variants and included gene expression studies 46, 47 , 48 , 49 , 50 , 51 . … We have, … Carvunis AR, Bannasch DL, Ostrander EA, Ideker T. (2020) Quantitative translation of dog-to-human aging by conserved …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… to engineer megabase changes to mammalian genomes in a locus-agnostic manner and v) Develop imaging technology to … require accurate manipulation of DNA sequences and gene expression as well as interrogation of the functional … entire field of epitranscriptomics research: a dearth of quantitative sequencing methods that can comprehensively map …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
News Release
Six new grants will support researchers for new computational approaches to search millions of genomic variants for disease susceptibility.
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.