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Educational Resources
Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules based on their size and electrical charge.
… Electrophoresis is a laboratory technique used to separate DNA, RNA, or protein molecules based on their size and … move faster than larger molecules. To determine the size of the molecules in a sample, standards of known sizes are separated on the same gel and then …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… Physical Map … A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest. … Chromosome, Gene, …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… Locus … A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. … within a genome (such as a gene or another DNA segment of interest), somewhat like a street address. The plural of …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals. … diseases that affect humans. They edit the genomes of animals, like mice and zebrafish, because animals have …
Educational Resources
A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique.
… Primer … A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) … polymerase chain reaction (PCR). In the PCR method, a pair of primers hybridizes with the sample DNA and defines the … that will be amplified, resulting in millions and millions of copies in a very short timeframe. Primers are also used in …
Event
The Journeys in Human Genetics and Genomics Colloquium is part of a training partnership between ASHG and NHGRI to showcase the depth and breadth of exciting scientific, clinical, and societal elements of human genetics and genomics at an introductory level as well as to illustrate the myriad associated career opportunities.
… July 2024 DNA Science and Human Genetics Lawrence Brody, Ph.D. … Institute   Slides Biography … July 2024 History of Genomics and the Human Genome Project Eric Green, M.D., … and breadth of exciting scientific, clinical, and societal elements of human genetics and genomics at an introductory …
Educational Resources
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes.
… Marker … A marker is a DNA sequence with a known physical location on a chromosome. … are used as signposts (or landmarks) in the construction of DNA and genome maps. Markers can also be used to track inheritance of traits or disease risk in families. … A marker is a DNA …
Educational Resources
Southern blotting is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample.
… is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample. … Deoxyribonucleic Acid (DNA), Electrophoresis, Northern Blot, Probe, Restriction … larger fragments. The DNA fragments are transferred out of the gel or matrix onto a solid membrane, which is then …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… by replacing it or disrupting it with an artificial piece of DNA. … Knocking out the activity of a gene provides valuable clues about what that gene …
News Release
Researchers from the NHGRI-funded Impact of Genomic Variation on Function Consortium are exploring how genomic variation affects genome function.
… Researchers from the NHGRI-funded Impact of Genomic Variation on Function Consortium are exploring how … genomic variation affects genome function. … While most DNA letters are the same amongst everyone, just under 0.5% … Carolina (UNC) at Chapel Hill, is investigating regulatory elements — regions of the genome that can dampen or amplify …