Division of Genomic Medicine

2021

• PAR-18-736 Investigator-Initiated Genomic Medicine Research (R21 Clinical Trial Optional)
  Application Due Date(s): June 20, 2018; October 19, 2018; June 20, 2019; October 21, 2019; June 19, 2020; October 20, 2020
  Expiration Date: January 23, 2021
   
• PAR-18-735 Investigator-Initiated Genomic Medicine Research (R01 Clinical Trial Optional)
  Application Due Date(s): June 20, 2018; October 19, 2018; June 20, 2019; October 21, 2019; June 19, 2020; October 20, 2020
  Expiration Date: January 23, 2021
   
• PA-18-867 Novel Approaches for Relating Genetic Variation to Function and Disease (R21 Clinical Trial Not Allowed)
  Open Date (Earliest Submission Date): September 16, 2018
  Expiration Date: July 17, 2021
   
• PA-18-868 Novel Approaches for Relating Genetic Variation to Function and Disease (R01 Clinical Trial Not Allowed)
  Open Date (Earliest Submission Date): September 5, 2018
  Expiration Date: July 6, 2021
   
• RFA-HG-20-049 Investigator-Initiated Research on Genetic Counseling Processes and Practices (R21, Clinical Trial Optional)
  Application Receipt Date(s): October 28, 2020 and July 8, 2021
  Expiration Date: July 9, 2021
   
• RFA-HG-20-048 Investigator-Initiated Research on Genetic Counseling Processes and Practices (R01, Clinical Trial Optional)
  Application Receipt Date(s): October 28, 2020 and July 8, 2021
  Expiration Date: July 9, 2021
  
  FAQ for Investigator-Initiated Research on Genetic Counseling Processes and Practices Funding Opportunity Announcements (RFA-HG-20-048 and RFA-HG-20-049)

2020

• RFA-HG-18-006 Genomic Innovator Award (R35 Clinical Trial Optional)
  Application Due Date(s): September 30, 2018; October 30, 2018; October 30, 2019; October 30, 2020
  Expiration Date: October 31, 2020
   
• NOT-OD-19-147 Notice of Special Interest: Administrative Supplements to NIH-funded T32 and TL1 Training Grants to Better Integrate Behavioral and Social Sciences (BSS) with other Health-Related Sciences
  Release Date: September 30, 2019
  Expiration Date: January 26, 2020
   
• RFA-HG-20-007 Mendelian Genomics Research Centers (U01 - Clinical Trial Optional)
  Application Due Date(s): April 15, 2020
  Expiration Date: April 16, 2020
   
• RFA-HG-20-008 Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)
  Application Due Date(s): April 15, 2020
  Expiration Date: April 16, 2020
   
• NOT-HG-20-031 Notice of Special Interest: Notice of Administrative Supplements for Stakeholder Engagement in Genomic Medicine Research
  First Available  Due Date(s): March 30, 2020
  Expiration Date: May 16, 2020
   
• NOT-HG-20-020 Notice of Special Interest (NOSI): Administrative Supplements for Development of Training Modules in Genomic Medicine for Health Care Professionals
  First Available Due Date: March 27, 2020
  Expiration Date: May 16, 2020
   
• NOT-HG-20-030 Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus
  First Available Due Date: April 03, 2020
  Expiration Date: May 16, 2020
   
• RFA-HG-20-001 Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01 Clinical Trial Not Allowed)
  Application Due Date(s): June 23, 2020
  Expiration Date: June 24, 2020
   
• RFA-HG-20-002 Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01 Clinical Trial Not Allowed)
  Application Due Date(s): June 23, 2020
  Expiration Date: June 24, 2020
   
• RFA-HG-20-039 Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project (U24 Clinical Trial Not Allowed)
  Application Due Date(s): November 13, 2020
  Expiration Date: November 14, 2020
   
• RFA-HD-21-008 Pediatric Biospecimen Procurement Center (BPC) Supporting the Developmental Gene Expression (dGTEx) Project (U24 Clinical Trial Not Allowed)
  Application Due Date(s): December 3, 2020
  Expiration Date: December 4, 2020

2019

• RFA-HG-19-015: The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network – Coordinating Center (U01 Clinical Trial Required)
  Application Due Date(s): August 2, 2019
  Expiration Date: August 3, 2019
   
• RFA-HG-19-014: The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network – Enhanced Diversity Clinical Sites (U01 Clinical Trial Required)
  Application Due Date(s): August 2, 2019
  Expiration Date: August 3, 2019
   
• RFA-HG-19-013: The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network – Clinical Sites(U01 Clinical Trial Required) 
  Application Due Date(s): August 2, 2019
  Expiration Date: August 3, 2019
  
  NOT-HG-19-023: Notice of Pre-Application Webinars for The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network, Clinical Sites (RFA-HG-19-013), Enhanced Diversity Clinical Sites (RFA-HG-19-014), and Coordinating Center (RFA-HG-19-015)

2017

• RFA-RM-17-015 Metabolomics Core for the Undiagnosed Diseases Network (UDN) Phase II (U01)
  Release Date: August 15, 2017
• RFA-RM-17-016 Sequencing Core(s) for the Undiagnosed Diseases Network (UDN) Phase II (U01)
  Release Date: August 15, 2017
• RFA-RM-17-017 Model Organisms Screening Center for the Undiagnosed Diseases Network (UDN) Phase II (U54)
  Release Date: August 15, 2017
  • Notice of Correction to the Award Budget for the RFA-RM-17-017 Model Organism Screening Center for the Undiagnosed Diseases Network (UDN) Phase II (U54)
    Release Date: August 15, 2017
     
• RFA-RM-17-018 Coordinating Center for the Undiagnosed Diseases Network (UDN) Phase II (U01)
   
• RFA-RM-17-019 Clinical Sites for the Undiagnosed Diseases Network (UDN) Phase II (U01)
  Release Date: August 15, 2017
   
• RFA-HG-17-011 The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL) (U24)
  Application Due Date(s): November 9, 2017
  Expiration Date: November 10, 2017
  • For additional information, please visit the NHGRI Genomic Data Science AnVIL webpage.
     
• NOT-HG-17-014 Notice of Applicant Information Webinar and Frequently Asked Questions (FAQ) for NHGRI IGNITE II RFAs: RFA-HG-17-008, RFA-HG-17-009 and RFA-HG-17-010
   
  • Frequently Asked Questions about IGNITE II
     
• RFA-HG-17-008 Implementing Genomics in Practice (IGNITE) II: Pragmatic Clinical Trials - Clinical Groups (U01) 
  Application Due Date(s): November 3, 2017
  Expiration Date: November 4, 2017
   
• RFA-HG-17-009 Implementing Genomics in Practice (IGNITE) II: Pragmatic Clinical Trials -Enhanced Diversity Clinical Groups (U01)
  Application Due Date(s): November 3, 2017
  Expiration Date: November 4, 2017
   
• RFA-HG-17-010 Implementing Genomics in Practice (IGNITE) II: Pragmatic Clinical Trials -Coordinating Center (U01)
  Application Due Date(s): November 3, 2017
  Expiration Date: November 4, 2017

2016

• RFA-HG-16-010 Clinical Sequencing Evidence-Generating Research (CSER2) - Clinical Sites (U01)
  • NOT-HG-16-021 Notice Announcing Pre-application Information Webinar for Clinical Sequencing Evidence-generating Research (CSER2) Requests For Applications (RFAs) and Frequently Asked Questions (FAQ) regarding Clinical Sequencing Funding Opportunities
    Release Date: May 6, 2016
     
• RFA-HG-16-011 Clinical Sequencing Evidence-Generating Research (CSER2) - Clinical Sites with Enhanced Diversity (U01)
  Release Date: May 6, 2016
   
• RFA-HG-16-012 Clinical Sequencing Evidence-Generating Research (CSER2) - Coordinating Center (U24)
  Release Date: May 6, 2016
   
• PAR-16-209 Investigator-Initiated Clinical Sequencing Research (R01) 
  Release Date: April 19, 2016
• PAR-16-274 Serious Adverse Drug Reaction Research (R21) 
  Release Date: May 19, 2016
• PAR-16-275 Serious Adverse Drug Reaction Research (R01) 
  Release Date: May 19, 2016
• PAR-16-435 Genomics of HIV/AIDS Drug Response and Co-Morbidities (R01) 
  Release Date: September 16, 2016

2015

• NOT-HG-15-014 Notice of Pre-Application Webinar for PA-14-015 "Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (Parent T32)" Related to the Creation of New NHGRI Postdoctoral Training Programs in Genomic Medicine Research
  Release Date: February 5, 2015

2014

• NOT-HG-14-017 Notice of NHGRI Participation in PA-14-015 "Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (Parent T32)" and Creation of New NHGRI Postdoctoral Training Programs in Genomic Medicine Research 
  Release Date: January 10, 2014
   
• RFA-HG-14-025 The Electronic Medical Records and Genomics (eMERGE) Network, Phase III - Study Investigators (U01)
  Release Date: July 9, 2014
   
• RFA-HG-14-026 The Electronic Medical Records and Genomics (eMERGE) Network, Phase III - Coordinating Center (U01)
  Release Date: July 17, 2014
   
• RFA-HG-14-027 The Electronic Medical Records and Genomics (eMERGE) Network, Phase III - Central Genome Sequencing and Genotyping Facility (U01)
  Release Date: July 17, 2014
   
  • Frequently Asked Questions for the Electronic Medical Records and Genomics (eMERGE) Network, Phase III RFAs

2013

• RFA-HD-13-010 Genomic Sequencing and Newborn Screening Disorders (U19)
  Release Date: August 9, 2012

2012

• RFA-HG-12-016 Clinically Relevant Genetic Variants Resource: A Unified Approach for Identifying Genetic Variants for Clinical Use (U01)
  Release Date: July 10, 2012
   
  • Frequently Asked Questions about RFA-HG-12-016
     
• RFA-HG-12-015 Population Architecture Using Genomics and Epidemiology (PAGE), Phase II Coordinating Center (U01)
  Release Date: June 20, 2012
   
• RFA-HG-12-010 Population Architecture Using Genomics and Epidemiology (PAGE), Phase II Study Investigators (U01)
  Release Date: June 20, 2012 
   
• NOT-HG-11-023 Notice of Intent to Publish a Request for Applications for The Electronic Medical Records and Genomics (eMERGE) Network - Pediatric Study Investigators
  Release Date: June 14, 2011 
   
• RFA-HG-12-007 Genomic Medicine Pilot Demonstration Projects Coordinating Center (U01)
  Release Date: April 3, 2012
   
• RFA-HG-12-006 Genomic Medicine Pilot Demonstration Projects (U01)
  Release Date: April 3, 2012
  • Frequently Asked Questions about the Genomic Medicine Pilot Demonstration Projects (U01)

2011

• NOT-HG-11-021 Notice of the National Human Genome Research Institute's Interest in Receiving Applications to Analyze and Develop Methods for X Chromosome Genome-wide Association (GWA) Data
  Release Date: June 1, 2011
   
• NOT-HG-11-009 Notice of Amendment and Re-issuance of Administrative Supplements for the Addition of Standard Measures to Population-based Genomic Research: The PhenX Toolkit
  Release Date: January 21, 2011
   
• RFA-HG-11-022 The Electronic Medical Records and Genomics (eMERGE) Network, Phase II - Pediatric Study Investigators (U01)
  Release Date: July 6, 2011

2010

• PAR-11-032 Methods and Approaches for Detection of Gene-Environment Interactions in Human Disease (R21)
  Release Date: November 12, 2010
   
• NOT-HG-11-001 Notice of Availability of Administrative Supplements for the Addition of Standard Measures to Population-Based Genomic Research: The PhenX Toolkit
  Release Date: October 8, 2010
   
• RFA HG-10-009 The Electronic Medical Records and Genomics (eMERGE) Network, Phase II - Study Investigators (U01)
  Release Date: July 16, 2010
   
• RFA HG-10-010 The Electronic Medical Records and Genomics (eMERGE) Network, Phase II - Coordinating Center (U01)
  Release Date: July 16, 2010

2009

• NOT-HG-08-013 Notice of Publication of FAQs Related to RFA-HG-08-004: Genome-wide Association Studies of Treatment Response in Randomized Clinical Trials - Study Investigators (U01) 
  Release Date: September 12, 2008
   
• NOT-HG-08-012 Correction for RFA-HG-08-005: Genome-wide Association Studies of Treatment Response in Randomized Clinical Trials - Coordinating Center (U01)
  Release Date: September 12, 2008
   
• NOT-OD-07-088 Policy for Sharing of Data Obtained in NIH Supported or Conducted Genome-Wide Association Studies (GWAS)
  Release Date: August 28, 2007
   
  • Developed following a public consultation process with interested stakeholders, the GWAS data-sharing policy will facilitate the research community's access to genotype-phenotype datasets from GWAS in a broad array of disease areas.
     
  • GWAS Oversight Structure
    A chart of the governance of data-release policy for GWAS

• NOT-OD-08-013 Implementation Guidance and Instructions for Applicants: Policy for Sharing of Data Obtained in NIH-Supported or Conducted Genome-Wide Association Studies (GWAS)
  Release Date: November 16, 2007
   
• RFA-HG-09-014 Comparing Design Approaches for Sequencing Disease-Associated Regions Found in Genome-Wide Association Studies (U01)
  Letters of Intent Receipt Date(s): November 12, 2009; Application Receipt Date: December 11, 2009
   
• RFA-HG-09-004 Follow-up Public Consultation to Inform the Design of a Possible Longitudinal Cohort Study of the Role of Genes and Environment in Health and Disease: Limited Competition (U01) 
  Letters of Intent Receipt Date(s): January 3, 2009; Application Receipt Date: February 3, 2009
   
• RFA-MH-09-120 Informing Systems Biology through Genetic Variation: The Genes, Environment and Health Initiative (R21)
  Letters of Intent Receipt Date(s): December 14, 2008; Application Receipt Date: January 14, 2009

2008

• NOT-CA-08-011 Administrative Supplements for Gene Identification Efforts: Replication and Fine-Mapping Studies for The Genes, Environment, and Health Initiative (GEI)
  Release Date: March 5, 2008
   
• RFA-CA-09-003 Replication and Fine-Mapping Studies for the Genes, Environment, and Health Initiative (GEI) (R01)
  Letters of Intent Receipt Date(s): October 24, 2008; Application Receipt Date: December 1, 2008
   
• RFA-DK-08-003 Implementation Planning Grants for Educational, Behavioral, or Social Studies for Translation of Genetic Factors in Common Diseases (U34)
  Letters of Intent Receipt Date(s): October 24, 2008; Application Receipt Date: November 25, 2008 
   
• RFA-DK-08-004 Translation of Common Disease Genetics into Clinical Applications (R21) 
  Letters of Intent Receipt Date(s): October 24, 2008; Application Receipt Date: November 25, 2008
   
• RFA-HG-08-004 Genome-wide Association Studies of Treatment Response in Randomized Clinical Trials - Study Investigators (U01) 
  Letters of Intent Receipt Date(s): October 13, 2008; Application Receipt Date: November 13, 2008
   
  • Frequently asked questions about RFA-HG-08-004
     
• RFA-HG-08-005 Genome-wide Association Studies of Treatment Response in Randomized Clinical Trials - Coordinating Center (U01) 
  Letters of Intent Receipt Date(s): October 13, 2008; Application Receipt Date: November 13, 2008
   
• RFA-DA-09-003 Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)
  Letters of Intent Receipt Date(s): September 17, 2008; Application Due Date(s): October 17, 2008
   
• RFA-DA-09-004 Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R03) 
  Letters of Intent Receipt Date(s): September 17, 2008; Application Due Date(s): October 17, 2008
   
  • Genomic Applications in Practice and Prevention (GAPP): Translation Programs in Education, Surveillance, and Policy [cdc.gov]

2007

• RFA-HG-07-005 Genome-Wide Studies in Biorepositories with Electronic Medical Record Data (U01)
   
  • Audio Recording of Pre-Application Technical Assistance Meeting for RFA-HG-07-005 [webmeeting.nih.gov]
     
• RFA-HG-07-006 High-Priority Phenotype and Exposure Measures for Cross-Study Analysis in Genome-Wide Association Studies (U01)
   
• RFA-HG-07-012 Genome-wide Association Studies in the Genes, Environment, and Health Initiative - Study Investigators (U01) (re-issue of RFA-HG-06-033)
   
• RFA-HG-07-014 Epidemiologic Investigation of Putative Causal Genetic Variants-Study Investigators (U01)
   
  • Frequently Asked Questions About RFA-HG-07-014
     
• RFA-HG-07-015 Epidemiologic Investigation of Putative Causal Genetic Variants-Coordinating Center (U01)
  
  NOT-LM-07-001 Genotype and Phenotype Data Now Available from dbGaP Database; Request Process Involves New Procedures for Principal Investigators and Signing Officials
   
• NOT-HG-08-001 Notice of Publication of FAQs Related to RFA-HG-07-014: Epidemiologic Investigation of Putative Causal Genetic Variants-Study Investigators (U01)
  Release Date: October 16, 2007
   
• NOT-HG-07-026 Notice to Allow Resubmissions to RFA-HG-07-012: Genome-wide Association Studies in the Genes, Environment, and Health Initiative - Study Investigators (U01)
   
• NOT-OD-07-066 Notice of Availability of the Data Access Request System for the Genetic Association Information Network (GAIN)

2006

• RFA-HG-06-014 Genome-wide Association Studies in the Genes and Environment Initiative - Genotyping Facilities (U01)
   
  • Frequently Asked Questions About RFA-HG-06-014
     
• RFA-HG-06-032 Genome-wide Association Studies in the Genes and Environment Initiative - Coordinating Center (U01)
   
  • Frequently Asked Questions About RFA-HG-06-32
     
• RFA-HG-06-033 Genome-wide Association Studies in the Genes and Environment Initiative - Study Investigators (U01)
   
  • Frequently Asked Questions About RFA-HG-06-33
     
• RFA-HG-06-008 Public Consultation to Inform the Design of Possible Large-Scale Studies of Genes and Environment in Common Disease (U01)