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Pharmacogenomics is a growing area of genomic medicine that uses a patient's genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.

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Epigenomics Fact Sheet

Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.

… of cancer, or to a failure of the immune system to destroy tumors. In a type of brain tumor called glioblastoma, doctors … that counteracts temozolomide. Glioblastoma patients whose tumors have such methylated genes are far more likely to …

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Knockout Mice Fact Sheet

A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.

… codes for a protein that normally suppresses the growth of tumors by arresting cell division. Humans born with mutations … with more than half of human cancers and often lead to tumors in a particular set of tissues. However, when the p53 gene is knocked out in mice, the animals develop tumors in a different array of tissues.Despite these …

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Biological Pathways Fact Sheet

A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.

… biological pathways and the genetic profiles of particular tumors, drug developers might be able to focus their … likely to repair the pathways affected in their particular tumors. … How do biological pathways work? … What are some …