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Funding Opportunities
Funding Opportunities for Investigator-Initiated Research in Computational Genomics and Data Science
The Computational Genomics and Data Science Program Announcements (PARs) invite applications for investigator-initiated research efforts fostering innovation in computational genomics, data science, statistics, bioinformatics, and data visualization and exploration.
… Annotation of Genomes via Phenotypic Convergence within Large Multi-species Alignments HG009299 JI, HONGKAI JOHNS … NATHAN UNIVERSITY OF VIRGINIA Novel methods for large-scale genomic interval comparison HG012558  LANGMEAD, … INSTITUTE Modeling Functional Elements using CRISPR Screening HG010753 QUINLAN, AARON R UNIVERSITY OF UTAH …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… technology currently being worked on in genomics including large-scale genetic sequencing, gene editing, artificial …
Research at NHGRI
The Center for Precision Health Research, formerly Medical Genomics and Metabolic Genetics Branch, studies how health and disease are related to genetic, genomic and metabolic variation.
… by applying tools ranging from high-throughput biologic methods, large scale informatics methods, classic bench laboratory …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… anemia and cystic fibrosis are inherited in families, what screening and testing options are available, and, for some … genes in a person or other organism. Due to the success of large-scale biology projects such as the sequencing of the human …
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… safe and effective. Two mRNA vaccines have been tested in large-scale clinical trials that included elderly and medically …
News Release
Researchers from the NHGRI-funded Impact of Genomic Variation on Function Consortium are exploring how genomic variation affects genome function.
… They are also finding new ways improve the sensitivity and scale of functional assays and to develop predictive models. … disease traits are amongst the most studied traits in large-scale genomic studies. These traits have been linked to … BEAN refines an existing approach called base editing screening, in which researchers create and study the …
Staff
Dr. Colin Fletcher is the program director in the Knockout Mouse Project (KOMP) in NHGRI's Extramural Research Program.
… Diego, where he oversaw the design and implementation of a large-scale mouse ENU mutagenesis screen. He has been working in …
Staff
Dr. Meru Sadhu is the head of the Systems Biology and Genome Engineering Section at the National Human Genome Research Institute. ​
… is immense, the section devises strategies to study large numbers of genetic differences in parallel. These … leverage the strengths of CRISPR technologies, large-scale oligonucleotide synthesis, the power of the yeast model … In addition to applying existing genome engineering methods, the section aims to further expand the reach of …
Staff
Dr. Wilson is the co-chief of and senior investigator in NHGRI's Computational and Statistical Genomics Branch.
… of the statistical properties of newly developed methods of genetic analysis for quantitative traits. … The … for sequence variants (tiled regression). In addition, the large and small sample statistical properties of these tests … (millions), e.g. high density SNP panels, and/or large-scale sequencing producing large numbers of rare sequence …
News Release
NHGRI convened geneticists, biologists, clinicians, bioinformatics specialists and more to provide expert advice on the future of its Genome Sequencing Program.
… into the clinic. In addition to the long-established Large-Scale Sequencing and Analysis Center (LSAC) program, the GSP … This means supporting research into new DNA sequencing methods and data analysis techniques and solving difficult …